MANF mesencephalic astrocyte derived neurotrophic factor [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: MANFprovided by VGNC
Official Full Name: mesencephalic astrocyte derived neurotrophic factorprovided by VGNC
Primary source: VGNC:VGNC:31171
See related: BGD:BT22333
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: ARMET
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 22

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	22	NC_037349.1 (49379788..49383627, complement)

Chromosome 22 - NC_037349.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in dopaminergic neuron differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in neuron projection development	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: mesencephalic astrocyte-derived neurotrophic factor

Names: arginine-rich protein; arginine-rich, mutated in early stage tumors

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001101211.2 → NP_001094681.1 mesencephalic astrocyte-derived neurotrophic factor precursor

See identical proteins and their annotated locations for NP_001094681.1

Status: PROVISIONAL

Source sequence(s)

BC149246

UniProtKB/Swiss-Prot

A6QPB9, P80513

Conserved Domains (1) summary

pfam10208
Location:26 → 170

Armet; Degradation arginine-rich protein for mis-folding