Format

Send to:

Choose Destination

MSX2 msh homeobox 2 [ Bos taurus (cattle) ]

Gene ID: 540230, updated on 28-Nov-2017
Official Symbol
MSX2provided by VGNC
Official Full Name
msh homeobox 2provided by VGNC
Primary source
VGNC:VGNC:31712
See related
BGD:BT28521; Ensembl:ENSBTAG00000013873
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
Location:
chromosome: 20
Exon count:
2
Annotation release Status Assembly Chr Location
105 current Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 20 AC_000177.1 (6360600..6365490)

Chromosome 20 - AC_000177.1Genomic Context describing neighboring genes Neighboring gene ribose-phosphate pyrophosphokinase 1 pseudogene Neighboring gene microRNA 584-6 Neighboring gene family with sequence similarity 169 member A Neighboring gene NSA2 ribosome biogenesis homolog (S. cerevisiae)

  • HTLV-I infection, organism-specific biosystem (from KEGG)
    HTLV-I infection, organism-specific biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
  • HTLV-I infection, conserved biosystem (from KEGG)
    HTLV-I infection, conserved biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
  • Neural Crest Differentiation, organism-specific biosystem (from WikiPathways)
    Neural Crest Differentiation, organism-specific biosystemGene regulatory network model of cranial neural crest cell (CNCC) development, adaped from PMID: 19575671. Most interactions in the model are proposed to regulate transcription of core factors involv...

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA polymerase II regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
transcription cofactor activity IEA
Inferred from Electronic Annotation
more info
 
transcription factor binding IEA
Inferred from Electronic Annotation
more info
 
transcription regulatory region DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
BMP signaling pathway involved in heart development IEA
Inferred from Electronic Annotation
more info
 
activation of meiosis IEA
Inferred from Electronic Annotation
more info
 
anterior/posterior pattern specification IEA
Inferred from Electronic Annotation
more info
 
bone trabecula formation IEA
Inferred from Electronic Annotation
more info
 
branching involved in mammary gland duct morphogenesis IEA
Inferred from Electronic Annotation
more info
 
cellular response to estradiol stimulus IEA
Inferred from Electronic Annotation
more info
 
chondrocyte development IEA
Inferred from Electronic Annotation
more info
 
embryonic forelimb morphogenesis IEA
Inferred from Electronic Annotation
more info
 
embryonic hindlimb morphogenesis IEA
Inferred from Electronic Annotation
more info
 
embryonic nail plate morphogenesis IEA
Inferred from Electronic Annotation
more info
 
enamel mineralization IEA
Inferred from Electronic Annotation
more info
 
endochondral bone growth IEA
Inferred from Electronic Annotation
more info
 
epithelial to mesenchymal transition involved in endocardial cushion formation IEA
Inferred from Electronic Annotation
more info
 
frontal suture morphogenesis IEA
Inferred from Electronic Annotation
more info
 
negative regulation of CREB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of cell proliferation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of fat cell differentiation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of keratinocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription from RNA polymerase II promoter ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of transcription regulatory region DNA binding IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
 
osteoblast development IEA
Inferred from Electronic Annotation
more info
 
osteoblast differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
outflow tract septum morphogenesis IEA
Inferred from Electronic Annotation
more info
 
positive regulation of BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 
positive regulation of mesenchymal cell apoptotic process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of osteoblast differentiation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of timing of catagen IEA
Inferred from Electronic Annotation
more info
 
signal transduction involved in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 
stem cell differentiation IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
wound healing, spreading of epidermal cells IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol IEA
Inferred from Electronic Annotation
more info
 
nuclear speck IEA
Inferred from Electronic Annotation
more info
 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079614.2NP_001073082.1  homeobox protein MSX-2

    See identical proteins and their annotated locations for NP_001073082.1

    Status: PROVISIONAL

    Source sequence(s)
    BC120248
    UniProtKB/Swiss-Prot
    Q0P5C3
    Related
    ENSBTAP00000018417.3, ENSBTAT00000018417.3
    Conserved Domains (1) summary
    pfam00046
    Location:145198
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_taurus_UMD_3.1.1 Primary Assembly

Genomic

  1. AC_000177.1 Reference Bos_taurus_UMD_3.1.1 Primary Assembly

    Range
    6360600..6365490
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Btau_5.0.1

Genomic

  1. NC_007318.6 Alternate Btau_5.0.1

    Range
    6391619..6396509
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center