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SLC25A12 solute carrier family 25 member 12 [ Bos taurus (domestic cattle) ]

Gene ID: 539494, updated on 5-Aug-2026
Official Symbol
SLC25A12provided by VGNC
Official Full Name
solute carrier family 25 member 12provided by VGNC
Primary source
VGNC:VGNC:34743
See related
BGD:BT14093; Ensembl:ENSBTAG00070005151
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
all
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Try the new Transcripts and proteins table
See SLC25A12 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (24637412..24736034)

Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene methionyl aminopeptidase type 1D, mitochondrial Neighboring gene histone acetyltransferase 1 Neighboring gene dynein cytoplasmic 1 intermediate chain 2 Neighboring gene small ribosomal subunit protein eS26-like

Genomic Sequence:
NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-aspartate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables L-glutamate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-glutamate transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in aspartate transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in malate-aspartate shuttle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial
Names
solute carrier family 25 (mitochondrial carrier, Aralar), member 12

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001101194.2 → NP_001094664.1  electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

    See identical proteins and their annotated locations for NP_001094664.1

    Status: PROVISIONAL

    Source sequence(s)
    BC148908
    UniProtKB/TrEMBL
    A0A3Q1M9V5, A6QNM9, F6RXI8
    Related
    ENSBTAP00070006662.1, ENSBTAT00070011803.1
    Conserved Domains (5) summary
    COG5126
    Location:147 → 217
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    cd15900
    Location:89 → 114
    EFh_MICU; EF-hand motif [structural motif]
    cl28896
    Location:89 → 158
    EFh_MICU; EF-hand, calcium binding motif, found in mitochondrial calcium uptake proteins MICU1, MICU2, MICU3, and similar proteins
    pfam00153
    Location:512 → 607
    Mito_carr; Mitochondrial carrier protein
    pfam13499
    Location:12 → 78
    EF-hand_7; EF-hand domain pair

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    24637412..24736034
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005202346.4 → XP_005202403.1  electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_005202403.1

    UniProtKB/TrEMBL
    A0A3Q1M9V5, A0AAA9SCC8
    Related
    ENSBTAP00070006655.1, ENSBTAT00070011796.1
    Conserved Domains (4) summary
    pfam00153
    Location:530 → 625
    Mito_carr; Mitochondrial carrier protein
    cd15900
    Location:107 → 132
    EFh_MICU; EF-hand motif [structural motif]
    cl25352
    Location:30 → 130
    EFh_PEF; The penta-EF hand (PEF) family
    cl28896
    Location:107 → 176
    EFh_MICU; EF-hand, calcium binding motif, found in mitochondrial calcium uptake proteins MICU1, MICU2, MICU3, and similar proteins

  2. XM_015474952.3 → XP_015330438.1  electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A3Q1M6G7
    Related
    ENSBTAP00070006651.1, ENSBTAT00070011792.1
    Conserved Domains (2) summary
    COG5126
    Location:58 → 128
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    pfam00153
    Location:423 → 518
    Mito_carr; Mitochondrial carrier protein
Nucleotide Protein Strain
Heading Accession and Version

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