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TGFB3 transforming growth factor beta 3 [ Bos taurus (domestic cattle) ]

Gene ID: 538957, updated on 5-Sep-2025
Official Symbol
TGFB3provided by VGNC
Official Full Name
transforming growth factor beta 3provided by VGNC
Primary source
VGNC:VGNC:35803
See related
BGD:BT10629; EnsemblRapid:ENSBTAG00070022041
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See TGFB3 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (87237854..87270920, complement)

Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104973250 Neighboring gene ergosterol biosynthesis 28 homolog Neighboring gene tubulin tyrosine ligase like 5 Neighboring gene intraflagellar transport 43 Neighboring gene uncharacterized LOC132346419 Neighboring gene uncharacterized LOC132346420 Neighboring gene transfer RNA tryptophan (anticodon CCA)

Genomic Sequence:
NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Modulation of the Effect of Transforming Growth Factor-β3 by Low-Intensity Pulsed Ultrasound on Scaffold-Free Dedifferentiated Articular Bovine Chondrocyte Tissues. Ting SY, et al. Tissue Eng Part C Methods, 2015 Oct. PMID 25915185
  2. Linkage of regulators of TGF-β activity in the fetal ovary to polycystic ovary syndrome. Hatzirodos N, et al. FASEB J, 2011 Jul. PMID 21411746, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transforming growth factor beta receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transforming growth factor beta receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
transforming growth factor beta-3 proprotein

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001101183.1 → NP_001094653.1  transforming growth factor beta-3 proprotein

    See identical proteins and their annotated locations for NP_001094653.1

    Status: PROVISIONAL

    Source sequence(s)
    BC149207
    UniProtKB/TrEMBL
    A6QP91
    Related
    ENSBTAP00070029492.1, ENSBTAT00070049604.1
    Conserved Domains (2) summary
    pfam00019
    Location:355 → 451
    TGF_beta; Transforming growth factor beta like domain
    pfam00688
    Location:66 → 272
    TGFb_propeptide; TGF-beta propeptide

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    87237854..87270920 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005212207.5 → XP_005212264.1  transforming growth factor beta-3 proprotein isoform X1

    See identical proteins and their annotated locations for XP_005212264.1

    UniProtKB/TrEMBL
    A6QP91
    Conserved Domains (2) summary
    pfam00019
    Location:355 → 451
    TGF_beta; Transforming growth factor beta like domain
    pfam00688
    Location:66 → 272
    TGFb_propeptide; TGF-beta propeptide

  2. XM_005212206.5 → XP_005212263.1  transforming growth factor beta-3 proprotein isoform X1

    See identical proteins and their annotated locations for XP_005212263.1

    UniProtKB/TrEMBL
    A6QP91
    Conserved Domains (2) summary
    pfam00019
    Location:355 → 451
    TGF_beta; Transforming growth factor beta like domain
    pfam00688
    Location:66 → 272
    TGFb_propeptide; TGF-beta propeptide
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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