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Pkd2l2 polycystic kidney disease 2-like 2 [ Mus musculus (house mouse) ]

Gene ID: 53871, updated on 22-Apr-2017
Official Symbol
Pkd2l2provided by MGI
Official Full Name
polycystic kidney disease 2-like 2provided by MGI
Primary source
MGI:MGI:1858231
See related
Ensembl:ENSMUSG00000014503
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TRPP5
Orthologs
Location:
18; 18 B1
Exon count:
18
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 18 NC_000084.6 (34408501..34442789)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (34569077..34602443)

Chromosome 18 - NC_000084.6Genomic Context describing neighboring genes Neighboring gene signal recognition particle 19 Neighboring gene receptor accessory protein 5 Neighboring gene SET translocation pseudogene Neighboring gene family with sequence similarity 13, member B Neighboring gene wingless-type MMTV integration site family, member 8A Neighboring gene NME/NM23 family member 5

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (3) 

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
detection of mechanical stimulus IBA
Inferred from Biological aspect of Ancestor
more info
 
ion transport IEA
Inferred from Electronic Annotation
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
polycystic kidney disease 2-like 2 protein
Names
Polycystin - L2
polycystin-2L2
polycystin-L2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163004.1NP_001156476.1  polycystic kidney disease 2-like 2 protein

    See identical proteins and their annotated locations for NP_001156476.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC090534, AK133423, BC138717
    Consensus CDS
    CCDS29127.1
    UniProtKB/Swiss-Prot
    Q9JLG4
    UniProtKB/TrEMBL
    Q3V056
    Related
    ENSMUSP00000127257.1, ENSMUST00000166156.7
    Conserved Domains (1) summary
    pfam08016
    Location:76497
    PKD_channel; Polycystin cation channel
  2. NM_016927.3NP_058623.2  polycystic kidney disease 2-like 2 protein

    See identical proteins and their annotated locations for NP_058623.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC090534, AC115305, BC138717
    Consensus CDS
    CCDS29127.1
    UniProtKB/Swiss-Prot
    Q9JLG4
    Related
    ENSMUSP00000014647.7, ENSMUST00000014647.7
    Conserved Domains (1) summary
    pfam08016
    Location:76497
    PKD_channel; Polycystin cation channel

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000084.6 Reference GRCm38.p4 C57BL/6J

    Range
    34408501..34442789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017317946.1XP_017173435.1  polycystic kidney disease 2-like 2 protein isoform X3

  2. XM_017317949.1XP_017173438.1  polycystic kidney disease 2-like 2 protein isoform X6

  3. XM_017317950.1XP_017173439.1  polycystic kidney disease 2-like 2 protein isoform X6

  4. XM_017317944.1XP_017173433.1  polycystic kidney disease 2-like 2 protein isoform X1

  5. XM_017317948.1XP_017173437.1  polycystic kidney disease 2-like 2 protein isoform X5

  6. XM_017317945.1XP_017173434.1  polycystic kidney disease 2-like 2 protein isoform X2

    UniProtKB/Swiss-Prot
    Q9JLG4
    Conserved Domains (1) summary
    pfam08016
    Location:76497
    PKD_channel; Polycystin cation channel
  7. XM_017317947.1XP_017173436.1  polycystic kidney disease 2-like 2 protein isoform X3

  8. XM_006526097.3XP_006526160.1  polycystic kidney disease 2-like 2 protein isoform X4

    Conserved Domains (1) summary
    pfam08016
    Location:78499
    PKD_channel; Polycystin cation channel
  9. XM_006526101.3XP_006526164.1  polycystic kidney disease 2-like 2 protein isoform X7

    Conserved Domains (1) summary
    pfam08016
    Location:78499
    PKD_channel; Polycystin cation channel
  10. XM_017317951.1XP_017173440.1  polycystic kidney disease 2-like 2 protein isoform X7

    Conserved Domains (1) summary
    pfam08016
    Location:78499
    PKD_channel; Polycystin cation channel
  11. XM_006526104.2XP_006526167.1  polycystic kidney disease 2-like 2 protein isoform X8

    Conserved Domains (1) summary
    pfam08016
    Location:78281
    PKD_channel; Polycystin cation channel
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