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P2RY13 purinergic receptor P2Y13 [ Homo sapiens (human) ]

Gene ID: 53829, updated on 23-Nov-2023


Official Symbol
P2RY13provided by HGNC
Official Full Name
purinergic receptor P2Y13provided by HGNC
Primary source
See related
Ensembl:ENSG00000181631 MIM:606380; AllianceGenome:HGNC:4537
Gene type
protein coding
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GPCR1; GPR86; GPR94; P2Y13; SP174; FKSG77
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. [provided by RefSeq, Sep 2008]
Broad expression in spleen (RPKM 21.1), appendix (RPKM 14.3) and 18 other tissues See more
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Genomic context

See P2RY13 in Genome Data Viewer
Exon count:
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (151326312..151329549, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (154077312..154080550, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (151044100..151047337, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 12L Neighboring gene purinergic receptor P2Y14 Neighboring gene Sharpr-MPRA regulatory region 3159 Neighboring gene SET pseudogene 11 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr3:151033994-151035193 Neighboring gene G protein-coupled receptor 87 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20701 Neighboring gene purinergic receptor P2Y12 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:151110665-151111260 Neighboring gene Sharpr-MPRA regulatory region 9761 Neighboring gene immunoglobulin superfamily member 10 Neighboring gene mitochondrial ribosomal protein L42 pseudogene 6

Genomic regions, transcripts, and products


  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018


GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled purinergic nucleotide receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
enables protein binding IPI
Inferred from Physical Interaction
more info
Process Evidence Code Pubs
involved_in G protein-coupled purinergic nucleotide receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
involved_in biological_process ND
No biological Data available
more info
involved_in cellular response to organic cyclic compound IEA
Inferred from Electronic Annotation
more info
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
located_in plasma membrane TAS
Traceable Author Statement
more info

General protein information

Preferred Names
P2Y purinoceptor 13
G protein-coupled receptor 86
G-protein coupled receptor 94
purinergic receptor P2Y, G-protein coupled, 13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_176894.3NP_795713.2  P2Y purinoceptor 13

    See identical proteins and their annotated locations for NP_795713.2

    Status: REVIEWED

    Source sequence(s)
    AC024886, DA676457
    Consensus CDS
    B2R827, Q05C50, Q6DKN4, Q8IUT5, Q8TDU7, Q9BPV8, Q9BY61
    ENSP00000320376.5, ENST00000325602.6
    Conserved Domains (1) summary
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly


  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    151326312..151329549 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006713664.1XP_006713727.1  P2Y purinoceptor 13 isoform X1

    Conserved Domains (1) summary
    PHA03087; G protein-coupled chemokine receptor-like protein; Provisional

Alternate T2T-CHM13v2.0


  1. NC_060927.1 Alternate T2T-CHM13v2.0

    154077312..154080550 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054346899.1XP_054202874.1  P2Y purinoceptor 13 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_023914.2: Suppressed sequence

    NM_023914.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript, which appears to include intronic sequence.