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SORCS1 sortilin related VPS10 domain containing receptor 1 [ Bos taurus (cattle) ]

Gene ID: 537536, updated on 3-Apr-2024

Summary

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Official Symbol
SORCS1provided by VGNC
Official Full Name
sortilin related VPS10 domain containing receptor 1provided by VGNC
Primary source
VGNC:VGNC:35130
See related
BGD:BT27419; Ensembl:ENSBTAG00000007948
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 26
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (27553215..28129844, complement)

Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene transfer RNA alanine (anticodon AGC) Neighboring gene uncharacterized LOC107131335 Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene uncharacterized LOC132343998 Neighboring gene charged multivesicular body protein 4B pseudogene Neighboring gene microRNA mir-2285k-4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in post-Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
VPS10 domain-containing receptor SorCS1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191207.2 → NP_001178136.2  VPS10 domain-containing receptor SorCS1 precursor

    Status: VALIDATED

    Source sequence(s)
    AAFC03007446, AAFC03007447, AAFC03021189, AAFC03021190, AAFC03021191, AAFC03045409, AAFC03095162, AAFC03124901, EE347278
    UniProtKB/TrEMBL
    A0A3Q1NNT1
    Related
    ENSBTAP00000057475.2, ENSBTAT00000076462.2
    Conserved Domains (3) summary
    smart00602
    Location:196 → 793
    VPS10; VPS10 domain
    pfam00801
    Location:807 → 880
    PKD; PKD domain
    pfam15901
    Location:638 → 793
    Sortilin_C; Sortilin, neurotensin receptor 3, C-terminal

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    27553215..28129844 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059881921.1 → XP_059737904.1  VPS10 domain-containing receptor SorCS1 isoform X4

  2. XM_024985735.2 → XP_024841503.1  VPS10 domain-containing receptor SorCS1 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1LPL1
    Related
    ENSBTAP00000058939.2, ENSBTAT00000076748.2
    Conserved Domains (3) summary
    smart00602
    Location:196 → 793
    VPS10; VPS10 domain
    pfam00801
    Location:807 → 880
    PKD; PKD domain
    cl26464
    Location:28 → 157
    Atrophin-1; Atrophin-1 family

  3. XM_059881920.1 → XP_059737903.1  VPS10 domain-containing receptor SorCS1 isoform X2

  4. XM_024985733.2 → XP_024841501.1  VPS10 domain-containing receptor SorCS1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1NNT1
    Conserved Domains (3) summary
    smart00602
    Location:196 → 793
    VPS10; VPS10 domain
    pfam00801
    Location:807 → 880
    PKD; PKD domain
    cl26464
    Location:28 → 157
    Atrophin-1; Atrophin-1 family
Nucleotide Protein Strain
Heading Accession and Version

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