ACVR1C activin A receptor type 1C [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: ACVR1Cprovided by VGNC
Official Full Name: activin A receptor type 1Cprovided by VGNC
Primary source: VGNC:VGNC:25594
See related: EnsemblRapid:ENSBTAG00070028787
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 2

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	2	NC_037329.1 (38753355..38838463)

Chromosome 2 - NC_037329.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

BZ943404 (e-PCR)
- UniSTS:474950

CSRD254 (e-PCR), detects polymorphism
- UniSTS:253557

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables activin receptor activity, type I	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in activin receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to growth factor stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in nervous system development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of activin receptor complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: activin receptor type-1C

Names: activin A receptor, type IC

NP_001179808.2

EC 2.7.11.30

XP_059731614.1

EC 2.7.11.30

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001192879.2 → NP_001179808.2 activin receptor type-1C precursor

See identical proteins and their annotated locations for NP_001179808.2

Status: PROVISIONAL

Source sequence(s)

NKLS02000002

UniProtKB/TrEMBL

A0AAA9SUC6, F1MMW7

Related

ENSBTAP00070039585.1, ENSBTAT00070065499.1

Conserved Domains (4) summary

cd14143
Location:198 → 485

STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

pfam01064
Location:26 → 99

Activin_recp; Activin types I and II receptor domain

pfam07714
Location:194 → 477

Pkinase_Tyr; Protein tyrosine kinase

pfam08515
Location:165 → 192

TGF_beta_GS; Transforming growth factor beta type I GS-motif