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B3gnt2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 [ Mus musculus (house mouse) ]

Gene ID: 53625, updated on 5-Jan-2023

Summary

Official Symbol
B3gnt2provided by MGI
Official Full Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2provided by MGI
Primary source
MGI:MGI:1889505
See related
Ensembl:ENSMUSG00000051650 AllianceGenome:MGI:1889505
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BGnT1; BGnT2; B3gnt1; BGnT-1; BGnT-2; B3Galt6; Beta3gnt
Summary
Predicted to enable N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity. Acts upstream of or within several processes, including axon guidance; cellular response to leukemia inhibitory factor; and sensory perception of smell. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and nose. Orthologous to human B3GNT2 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 23.2), colon adult (RPKM 14.5) and 25 other tissues See more
Orthologs
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Genomic context

See B3gnt2 in Genome Data Viewer
Location:
11 A3.2; 11 14.22 cM
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (22784739..22810336, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (22834739..22860336, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene methionine aminopeptidase 2 pseudogene Neighboring gene ribosomal protein S16 pseudogene Neighboring gene predicted gene, 24917 Neighboring gene COMM domain containing 1 Neighboring gene zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2
Names
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
beta-1,3-Gn-T1
beta-1,3-Gn-T2
beta-1,3-N-acetylglucosaminyltransferase 1
beta-1,3-N-acetylglucosaminyltransferase 2
beta3Gn-T1
beta3Gn-T2
NP_001162585.1
NP_058584.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001169114.1NP_001162585.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

    See identical proteins and their annotated locations for NP_001162585.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses a different exon for its 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL772364
    Consensus CDS
    CCDS24471.1
    UniProtKB/Swiss-Prot
    Q91V18, Q9Z222
    UniProtKB/TrEMBL
    Q3TVJ9
    Related
    ENSMUSP00000053528.4, ENSMUST00000055549.4
    Conserved Domains (1) summary
    cl21608
    Location:156345
    Galactosyl_T; Galactosyltransferase
  2. NM_016888.5NP_058584.3  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

    See identical proteins and their annotated locations for NP_058584.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL772364
    Consensus CDS
    CCDS24471.1
    UniProtKB/Swiss-Prot
    Q91V18, Q9Z222
    UniProtKB/TrEMBL
    Q3TVJ9
    Related
    ENSMUSP00000060247.11, ENSMUST00000062844.11
    Conserved Domains (1) summary
    cl21608
    Location:156345
    Galactosyl_T; Galactosyltransferase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    22784739..22810336 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)