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Vamp5 vesicle-associated membrane protein 5 [ Mus musculus (house mouse) ]

Gene ID: 53620, updated on 13-Oct-2022

Summary

Official Symbol
Vamp5provided by MGI
Official Full Name
vesicle-associated membrane protein 5provided by MGI
Primary source
MGI:MGI:1858622
See related
Ensembl:ENSMUSG00000073002 AllianceGenome:MGI:1858622
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Camp
Summary
Acts upstream of or within Golgi to plasma membrane protein transport and skeletal muscle tissue development. Located in several cellular components, including cytoplasmic vesicle; intercalated disc; and perinuclear region of cytoplasm. Is integral component of organelle membrane and integral component of plasma membrane. Orthologous to human VAMP5 (vesicle associated membrane protein 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in liver E14.5 (RPKM 12.4), liver E14 (RPKM 12.0) and 28 other tissues See more
Orthologs
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Genomic context

See Vamp5 in Genome Data Viewer
Location:
6; 6 C1
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (72345032..72357451, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (72368049..72380468, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 0610030E20 gene Neighboring gene transmembrane protein 150A Neighboring gene ring finger protein 181 Neighboring gene predicted gene, 52494 Neighboring gene vesicle-associated membrane protein 8 Neighboring gene gamma-glutamyl carboxylase

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in cell surface ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasmic vesicle membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in intercalated disc IDA
Inferred from Direct Assay
more info
PubMed 
located_in late endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in organelle membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in trans-Golgi network ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
vesicle-associated membrane protein 5
Names
VAMP-5
myobrevin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080742.2NP_001074211.1  vesicle-associated membrane protein 5

    See identical proteins and their annotated locations for NP_001074211.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC116115, AK009266
    Consensus CDS
    CCDS39513.1
    UniProtKB/Swiss-Prot
    Q9Z2P8
    UniProtKB/TrEMBL
    A0A8C6GP72, Q791P0
    Related
    ENSMUSP00000073852.4, ENSMUST00000074231.6
    Conserved Domains (2) summary
    cd15872
    Location:570
    R-SNARE_VAMP5; SNARE motif of VAMP5
    pfam00957
    Location:479
    Synaptobrevin; Synaptobrevin
  2. NM_016872.4NP_058568.1  vesicle-associated membrane protein 5

    See identical proteins and their annotated locations for NP_058568.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC116115, BC086925
    Consensus CDS
    CCDS39513.1
    UniProtKB/Swiss-Prot
    Q9Z2P8
    UniProtKB/TrEMBL
    A0A8C6GP72, Q5M9K2, Q791P0
    Related
    ENSMUSP00000098843.4, ENSMUST00000101285.10
    Conserved Domains (2) summary
    cd15872
    Location:570
    R-SNARE_VAMP5; SNARE motif of VAMP5
    pfam00957
    Location:479
    Synaptobrevin; Synaptobrevin

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    72345032..72357451 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)