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Jafrac1 thioredoxin peroxidase 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 53578, updated on 19-Aug-2018

Summary

Official Symbol
Jafrac1provided by FlyBase
Official Full Name
thioredoxin peroxidase 1provided by FlyBase
Primary source
FLYBASE:FBgn0040309
Locus tag
Dmel_CG1633
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
1633; CG1633; cTPx; Dmel\CG1633; DmTPx-1; dPrx I; Dpx-4783; DPx-4783; DPx4783; Jafrac; JAFRAC 1; jafrac1; jf1; PRDX1_DROME; Prx; Prx4783; SSP5111; T20

Genomic context

See Jafrac1 in Genome Data Viewer
Location:
11E11-11E11; 1-42 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13329824..13331994)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13223857..13226027)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Inositol 1,4,5-triphosphate kinase 2 Neighboring gene ncRNA Neighboring gene Ribosomal protein S15Aa

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
thioredoxin peroxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
thioredoxin peroxidase activity IDA
Inferred from Direct Assay
more info
PubMed 
thioredoxin peroxidase activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
cell adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell redox homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell redox homeostasis IDA
Inferred from Direct Assay
more info
PubMed 
determination of adult lifespan IMP
Inferred from Mutant Phenotype
more info
PubMed 
germ cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
germ cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
hydrogen peroxide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hydrogen peroxide catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
response to oxidative stress IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to starvation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
thioredoxin peroxidase 1
Names
CG1633-PA
CG1633-PB
CG1633-PC
CG1633-PD
CG1633-PE
Jafrac1-PA
Jafrac1-PB
Jafrac1-PC
Jafrac1-PD
Jafrac1-PE
peroxidase
peroxiredoxin
peroxiredoxin 1
peroxiredoxin 4783
peroxiredoxin I
thioredoxin peroxidase
NP_001285202.1
NP_001285203.1
NP_001285204.1
NP_477510.1
NP_727689.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    13329824..13331994
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298274.1NP_001285203.1  thioredoxin peroxidase 1, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285203.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9V3P0
    UniProtKB/TrEMBL
    X2JF59
    Related
    FBpp0308757.1, FBtr0339700
    Conserved Domains (2) summary
    PTZ00253
    Location:3193
    PTZ00253; tryparedoxin peroxidase; Provisional
    cd03015
    Location:4175
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...
  2. NM_167359.2NP_727689.1  thioredoxin peroxidase 1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_727689.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9V3P0
    UniProtKB/TrEMBL
    X2JF59
    Related
    FBpp0073594.1, FBtr0073763
    Conserved Domains (2) summary
    PTZ00253
    Location:3193
    PTZ00253; tryparedoxin peroxidase; Provisional
    cd03015
    Location:4175
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...
  3. NM_058162.3NP_477510.1  thioredoxin peroxidase 1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477510.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9V3P0
    UniProtKB/TrEMBL
    X2JF59
    Related
    FBpp0073595.1, FBtr0073764
    Conserved Domains (2) summary
    PTZ00253
    Location:3193
    PTZ00253; tryparedoxin peroxidase; Provisional
    cd03015
    Location:4175
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...
  4. NM_001298273.1NP_001285202.1  thioredoxin peroxidase 1, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285202.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9V3P0
    UniProtKB/TrEMBL
    X2JF59
    Related
    FBpp0308756.1, FBtr0339699
    Conserved Domains (2) summary
    PTZ00253
    Location:3193
    PTZ00253; tryparedoxin peroxidase; Provisional
    cd03015
    Location:4175
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...
  5. NM_001298275.1NP_001285204.1  thioredoxin peroxidase 1, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285204.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9V3P0
    UniProtKB/TrEMBL
    X2JF59
    Related
    FBpp0311371.1, FBtr0345161
    Conserved Domains (2) summary
    PTZ00253
    Location:3193
    PTZ00253; tryparedoxin peroxidase; Provisional
    cd03015
    Location:4175
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...
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