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PNPLA8 patatin like phospholipase domain containing 8 [ Bos taurus (domestic cattle) ]

Gene ID: 535496, updated on 4-Feb-2026
Official Symbol
PNPLA8provided by VGNC
Official Full Name
patatin like phospholipase domain containing 8provided by VGNC
Primary source
VGNC:VGNC:33095
See related
BGD:BT20351; EnsemblRapid:ENSBTAG00070022716
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
all
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See PNPLA8 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (49588047..49638409, complement)

Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132345089 Neighboring gene neuronal cell adhesion molecule Neighboring gene uncharacterized LOC112446376 Neighboring gene G protein-coupled receptor 141-like

Genomic Sequence:
NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Confirmation of a non-synonymous SNP in PNPLA8 as a candidate causal mutation for Weaver syndrome in Brown Swiss cattle. Kunz E, et al. Genet Sel Evol, 2016 Mar 18. PMID 26992691, Free PMC Article
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in arachidonate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
calcium-independent phospholipase A2-gamma
XP_005205501.2
XP_005205502.2
XP_024846821.1
XP_059741842.1
XP_059741843.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    49588047..49638409 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005205445.4 → XP_005205502.2  calcium-independent phospholipase A2-gamma isoform X2

    UniProtKB/TrEMBL
    A0AAA9SYU3, A0AAA9TJT8
    Related
    ENSBTAP00070030571.1, ENSBTAT00070051170.1
    Conserved Domains (2) summary
    cd07211
    Location:385 → 691
    Pat_PNPLA8; Patatin-like phospholipase domain containing protein 8
    pfam07052
    Location:171 → 234
    Hep_59; Hepatocellular carcinoma-associated antigen 59

  2. XM_005205444.5 → XP_005205501.2  calcium-independent phospholipase A2-gamma isoform X1

    UniProtKB/TrEMBL
    A0AAA9TJT8, E1BE78
    Related
    ENSBTAP00070030593.1, ENSBTAT00070051195.1
    Conserved Domains (2) summary
    cd07211
    Location:437 → 743
    Pat_PNPLA8; Patatin-like phospholipase domain containing protein 8
    pfam07052
    Location:223 → 286
    Hep_59; Hepatocellular carcinoma-associated antigen 59

  3. XM_059885859.1 → XP_059741842.1  calcium-independent phospholipase A2-gamma isoform X2

    UniProtKB/TrEMBL
    A0AAA9SYU3, A0AAA9TJT8
    Related
    ENSBTAP00070030560.1, ENSBTAT00070051160.1

  4. XM_024991053.2 → XP_024846821.1  calcium-independent phospholipase A2-gamma isoform X2

    UniProtKB/TrEMBL
    A0AAA9SYU3, A0AAA9TJT8
    Conserved Domains (2) summary
    cd07211
    Location:385 → 691
    Pat_PNPLA8; Patatin-like phospholipase domain containing protein 8
    pfam07052
    Location:171 → 234
    Hep_59; Hepatocellular carcinoma-associated antigen 59

  5. XM_059885860.1 → XP_059741843.1  calcium-independent phospholipase A2-gamma isoform X2

    UniProtKB/TrEMBL
    A0AAA9SYU3, A0AAA9TJT8
Nucleotide Protein Strain
Heading Accession and Version

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