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SIRT6 sirtuin 6 [ Bos taurus (cattle) ]

Gene ID: 535416, updated on 27-Aug-2018

Summary

Official Symbol
SIRT6provided by VGNC
Official Full Name
sirtuin 6provided by VGNC
Primary source
VGNC:VGNC:34635
See related
BGD:BT19067; Ensembl:ENSBTAG00000019909
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs

Genomic context

See SIRT6 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 7 NC_037334.1 (19856934..19865253)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 7 AC_000164.1 (21079093..21087378)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene Epstein-Barr virus induced 3 Neighboring gene ankyrin repeat domain 24 Neighboring gene cAMP responsive element binding protein 3 like 3 Neighboring gene mitogen-activated protein kinase kinase 2

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

General protein information

Preferred Names
NAD-dependent protein deacetylase sirtuin-6
NP_001091553.1
XP_010805287.1
XP_015327557.1
XP_024850168.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098084.1NP_001091553.1  NAD-dependent protein deacetylase sirtuin-6

    See identical proteins and their annotated locations for NP_001091553.1

    Status: PROVISIONAL

    Source sequence(s)
    BC140592
    UniProtKB/TrEMBL
    A5D7K6
    Related
    ENSBTAP00000026521.5, ENSBTAT00000026521.5
    Conserved Domains (1) summary
    cd01410
    Location:45257
    SIRT7; SIRT7: Eukaryotic and prokaryotic group (class4) which includes human sirtuin SIRT6, SIRT7, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent ...

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    19856934..19865253
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015472071.2XP_015327557.1  NAD-dependent protein deacetylase sirtuin-6 isoform X1

    Conserved Domains (1) summary
    cl00195
    Location:109239
    SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...
  2. XM_010806985.3XP_010805287.1  NAD-dependent protein deacetylase sirtuin-6 isoform X2

    Conserved Domains (1) summary
    cl00195
    Location:11203
    SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...
  3. XM_024994400.1XP_024850168.1  NAD-dependent protein deacetylase sirtuin-6 isoform X3

    Conserved Domains (1) summary
    cl00195
    Location:53183
    SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...
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