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AKT2 AKT serine/threonine kinase 2 [ Bos taurus (domestic cattle) ]

Gene ID: 534923, updated on 30-Jan-2025
Official Symbol
AKT2provided by VGNC
Official Full Name
AKT serine/threonine kinase 2provided by VGNC
Primary source
VGNC:VGNC:25799
See related
BGD:BT10099; EnsemblRapid:ENSBTAG00070018643
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See AKT2 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (49627363..49674927, complement)

Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase 10 Neighboring gene tetratricopeptide repeat domain 9B Neighboring gene cyclin P Neighboring gene chromosome 18 C19orf47 homolog Neighboring gene phospholipase D family member 3 Neighboring gene homeodomain interacting protein kinase 4

Genomic Sequence:
NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Spatial coordination of actin polymerization and ILK-Akt2 activity during endothelial cell migration. Fan Y, et al. Dev Cell, 2009 May. PMID 19460343, Free PMC Article
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
RAC-beta serine/threonine-protein kinase
NP_001193075.1
XP_005219038.1
XP_005219039.1
XP_059732814.1
XP_059732815.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001206146.2 → NP_001193075.1  RAC-beta serine/threonine-protein kinase

    See identical proteins and their annotated locations for NP_001193075.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000018
    UniProtKB/TrEMBL
    A0A3Q1MN42, A0A3Q1NH21, E1B9D1
    Related
    ENSBTAP00070025128.1, ENSBTAT00070042138.1
    Conserved Domains (2) summary
    cd05595
    Location:156 → 478
    STKc_PKB_beta; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B beta (also called Akt2)
    cd01241
    Location:4 → 111
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    49627363..49674927 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005218981.5 → XP_005219038.1  RAC-beta serine/threonine-protein kinase isoform X1

    See identical proteins and their annotated locations for XP_005219038.1

    UniProtKB/TrEMBL
    A0A3Q1MN42, A0A3Q1NH21, E1B9D1
    Conserved Domains (2) summary
    cd05595
    Location:156 → 478
    STKc_PKB_beta; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B beta (also called Akt2)
    cd01241
    Location:4 → 111
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain

  2. XM_059876831.1 → XP_059732814.1  RAC-beta serine/threonine-protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MN42, A0A3Q1NH21, E1B9D1

  3. XM_059876832.1 → XP_059732815.1  RAC-beta serine/threonine-protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MN42, A0A3Q1NH21, E1B9D1

  4. XM_005218982.5 → XP_005219039.1  RAC-beta serine/threonine-protein kinase isoform X1

    See identical proteins and their annotated locations for XP_005219039.1

    UniProtKB/TrEMBL
    A0A3Q1MN42, A0A3Q1NH21, E1B9D1
    Conserved Domains (2) summary
    cd05595
    Location:156 → 478
    STKc_PKB_beta; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B beta (also called Akt2)
    cd01241
    Location:4 → 111
    PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
Nucleotide Protein Strain
Heading Accession and Version

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