Format

Send to:

Choose Destination

ITIH5 inter-alpha-trypsin inhibitor heavy chain 5 [ Bos taurus (cattle) ]

Gene ID: 534787, updated on 9-Jan-2020

Summary

Official Symbol
ITIH5provided by VGNC
Official Full Name
inter-alpha-trypsin inhibitor heavy chain 5provided by VGNC
Primary source
VGNC:VGNC:30337
See related
Ensembl:ENSBTAG00000013004
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs

Genomic context

See ITIH5 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 13 NC_037340.1 (16200829..16281662)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 13 AC_000170.1 (16278275..16407973)

Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene inter-alpha-trypsin inhibitor heavy chain 2 Neighboring gene eukaryotic initiation factor 4A-II pseudogene Neighboring gene uncharacterized LOC107133028 Neighboring gene uncharacterized LOC101903501 Neighboring gene uncharacterized LOC112449255

Genomic regions, transcripts, and products

General gene information

Homology

Clone Names

  • MGC155215

Gene Ontology Provided by GOA

Function Evidence Code Pubs
serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
hyaluronan metabolic process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
inter-alpha-trypsin inhibitor heavy chain H5
Names
ITI heavy chain H5
ITI-HC5
inter-alpha (globulin) inhibitor H5
inter-alpha-inhibitor heavy chain 5
inter-alpha-trypsin inhibitor heavy chain family member 5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001102516.1NP_001095986.1  inter-alpha-trypsin inhibitor heavy chain H5 precursor

    See identical proteins and their annotated locations for NP_001095986.1

    Status: PROVISIONAL

    Source sequence(s)
    BC133544
    UniProtKB/Swiss-Prot
    A2VE29
    Related
    ENSBTAP00000045691.3, ENSBTAT00000048699.4
    Conserved Domains (3) summary
    cd01461
    Location:292473
    vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
    pfam06668
    Location:718907
    ITI_HC_C; Inter-alpha-trypsin inhibitor heavy chain C-terminus
    pfam08487
    Location:51157
    VIT; Vault protein inter-alpha-trypsin domain

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037340.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    16200829..16281662
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center