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RFX2 regulatory factor X2 [ Bos taurus (domestic cattle) ]

Gene ID: 534475, updated on 24-Aug-2024

Summary

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Official Symbol
RFX2provided by VGNC
Official Full Name
regulatory factor X2provided by VGNC
Primary source
VGNC:VGNC:33894
See related
Ensembl:ENSBTAG00000017661
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (18305239..18398184)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132345711 Neighboring gene MLLT1 super elongation complex subunit Neighboring gene acyl-CoA synthetase bubblegum family member 2 Neighboring gene uncharacterized LOC100848538 Neighboring gene RAN binding protein 3 Neighboring gene calcyphosine Neighboring gene vimentin type intermediate filament associated coiled-coil protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC148739

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA-binding protein RFX2
Names
regulatory factor X 2
regulatory factor X, 2 (influences HLA class II expression)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001102172.1 → NP_001095642.1  DNA-binding protein RFX2

    See identical proteins and their annotated locations for NP_001095642.1

    Status: PROVISIONAL

    Source sequence(s)
    BC148113
    UniProtKB/Swiss-Prot
    A6QLW9
    UniProtKB/TrEMBL
    A0A3Q1LXX1
    Related
    ENSBTAP00000023492.5, ENSBTAT00000023492.7
    Conserved Domains (2) summary
    pfam02257
    Location:205 → 277
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:32 → 158
    RFX1_trans_act; RFX1 transcription activation region

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    18305239..18398184
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024994391.2 → XP_024850159.1  DNA-binding protein RFX2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LX23, A0A3Q1MQZ4
    Related
    ENSBTAP00000056790.1, ENSBTAT00000068035.2
    Conserved Domains (2) summary
    pfam02257
    Location:205 → 277
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:4 → 158
    RFX1_trans_act; RFX1 transcription activation region

  2. XM_024994394.2 → XP_024850162.1  DNA-binding protein RFX2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LX23
    Conserved Domains (2) summary
    pfam02257
    Location:176 → 252
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:4 → 158
    RFX1_trans_act; RFX1 transcription activation region

  3. XM_024994396.2 → XP_024850164.1  DNA-binding protein RFX2 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1LX23
    Related
    ENSBTAP00000062015.2, ENSBTAT00000085247.2
    Conserved Domains (2) summary
    pfam02257
    Location:175 → 247
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:31 → 128
    RFX1_trans_act; RFX1 transcription activation region

  4. XM_024994392.2 → XP_024850160.1  DNA-binding protein RFX2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LX23, A0A3Q1MQZ4
    Conserved Domains (2) summary
    pfam02257
    Location:205 → 277
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:4 → 158
    RFX1_trans_act; RFX1 transcription activation region

  5. XM_059888288.1 → XP_059744271.1  DNA-binding protein RFX2 isoform X4

    UniProtKB/TrEMBL
    A0A3Q1LX23
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A6QLW9.1 GenPept UniProtKB/Swiss-Prot:A6QLW9

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