Format

Send to:

Choose Destination

RecQ4 RecQ4 helicase [ Drosophila melanogaster (fruit fly) ]

Gene ID: 53438, updated on 8-Jul-2018
Official Symbol
RecQ4provided by FlyBase
Official Full Name
RecQ4 helicaseprovided by FlyBase
Primary source
FLYBASE:FBgn0040290
Locus tag
Dmel_CG7487
Gene type
protein coding
RNA name
RecQ4 helicase
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cg7487; CG7487; Dmel\CG7487; DmRECQ4; dRecQ4; RECQL4
See RecQ4 in Genome Data Viewer
Location:
66B10-66B10; 3-22 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8170640..8175978, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8163740..8169078, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene N-myristoyl transferase Neighboring gene methuselah-like 7

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATP-dependent 3'-5' DNA helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATP-dependent 3'-5' DNA helicase activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA helicase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
DNA-dependent ATPase activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA-dependent ATPase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
annealing helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
bubble DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
four-way junction helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
helicase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
oxidized purine DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
single-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
single-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
telomeric D-loop binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA duplex unwinding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA duplex unwinding IDA
Inferred from Direct Assay
more info
PubMed 
DNA recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA repair ISS
Inferred from Sequence or Structural Similarity
more info
 
DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
DNA replication ISS
Inferred from Sequence or Structural Similarity
more info
 
DNA rewinding IDA
Inferred from Direct Assay
more info
PubMed 
base-excision repair IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
base-excision repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell division IMP
Inferred from Mutant Phenotype
more info
PubMed 
double-strand break repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
double-strand break repair via homologous recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
eggshell chorion gene amplification IMP
Inferred from Mutant Phenotype
more info
PubMed 
larval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
oogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of G2/M transition of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of G2/M transition of mitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
telomeric D-loop disassembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with chromatin IDA
Inferred from Direct Assay
more info
PubMed 
chromosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chromosome, telomeric region IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
RecQ4 helicase
Names
CG7487-PA
RecQ4-PA
NP_652607.1

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    8170640..8175978 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_144350.2NP_652607.1  RecQ4 helicase [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652607.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VSE6
    Related
    FBpp0076452.1, FBtr0076729
    Conserved Domains (3) summary
    COG0514
    Location:8641218
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
    cd00079
    Location:10731216
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00270
    Location:8721039
    DEAD; DEAD/DEAH box helicase
Support Center