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MAPK9 mitogen-activated protein kinase 9 [ Bos taurus (cattle) ]

Gene ID: 534125, updated on 20-Jun-2023

Summary

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Official Symbol
MAPK9provided by VGNC
Official Full Name
mitogen-activated protein kinase 9provided by VGNC
Primary source
VGNC:VGNC:31227
See related
BGD:BT18224; EnsemblRapid:ENSBTAG00000004709
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
JNK2
Orthologs
human mouse all
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Genomic context

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See MAPK9 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 7 NC_037334.1 (919314..987439)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 7 AC_000164.1 (826695..895121)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene CCR4-NOT transcription complex subunit 6 Neighboring gene transfer RNA histidin (anticodon AUG) Neighboring gene glutamine-fructose-6-phosphate transaminase 2 Neighboring gene RasGEF domain family member 1C Neighboring gene 60S ribosomal protein L21-like Neighboring gene zinc finger CCHC domain-containing protein 9-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Theileria highjacks JNK2 into a complex with the macroschizont GPI (GlycosylPhosphatidylInositol)-anchored surface protein p104. Latré De Laté P, et al. Cell Microbiol, 2019 Mar. PMID 30412643
  2. JNK2 promotes endothelial cell alignment under flow. Hahn C, et al. PLoS One, 2011. PMID 21909388, Free PMC Article
  3. c-Jun N-terminal kinase 2 phosphorylates endothelial nitric oxide synthase at serine 116 and regulates nitric oxide production. Park JH, et al. Biochem Biophys Res Commun, 2012 Jan 6. PMID 22155232
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. At the parasite's surface, JNK2 forms a complex with p104, a GPI-(GlycosylPhosphatidylInositol)-anchor Theileria annulata plasma membrane protein. Theileria annulata sequestration of JNK2 contributes to both survival and dissemination of Theileria-transformed macrophages.
    Title: Theileria highjacks JNK2 into a complex with the macroschizont GPI (GlycosylPhosphatidylInositol)-anchored surface protein p104.
  2. activation in response to laminar shear stress is biphasic, with an early peak and a later peak.
    Title: JNK2 promotes endothelial cell alignment under flow.
  3. this study indicates that JNK2 is a physiological kinase responsible for eNOS-Ser(116) phosphorylation and regulates NO production.
    Title: c-Jun N-terminal kinase 2 phosphorylates endothelial nitric oxide synthase at serine 116 and regulates nitric oxide production.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC137545

General protein information

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Preferred Names
mitogen-activated protein kinase 9
NP_001039834.1
XP_005208427.1
XP_005208428.1
XP_005208432.1
XP_005208433.1
XP_024850141.1
XP_024850142.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001046369.1 → NP_001039834.1  mitogen-activated protein kinase 9

    See identical proteins and their annotated locations for NP_001039834.1

    Status: PROVISIONAL

    Source sequence(s)
    BC112747
    UniProtKB/TrEMBL
    Q2KI72
    Related
    ENSBTAP00000006183.5, ENSBTAT00000006183.6
    Conserved Domains (1) summary
    cl21453
    Location:25 → 275
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    919314..987439
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005208371.4 → XP_005208428.1  mitogen-activated protein kinase 9 isoform X5

    See identical proteins and their annotated locations for XP_005208428.1

    UniProtKB/TrEMBL
    A0A3Q1LJU7
    Related
    ENSBTAP00000056751.2, ENSBTAT00000082454.2
    Conserved Domains (1) summary
    cd07850
    Location:25 → 360
    STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

  2. XM_005208375.4 → XP_005208432.1  mitogen-activated protein kinase 9 isoform X2

    See identical proteins and their annotated locations for XP_005208432.1

    Related
    ENSBTAP00000061184.2, ENSBTAT00000083233.2
    Conserved Domains (1) summary
    cd07850
    Location:25 → 360
    STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

  3. XM_005208370.4 → XP_005208427.1  mitogen-activated protein kinase 9 isoform X1

    See identical proteins and their annotated locations for XP_005208427.1

    UniProtKB/TrEMBL
    A0A3Q1LVH0
    Related
    ENSBTAP00000095761.1, ENSBTAT00000105686.1
    Conserved Domains (1) summary
    cd07850
    Location:25 → 360
    STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

  4. XM_005208376.2 → XP_005208433.1  mitogen-activated protein kinase 9 isoform X3

    Conserved Domains (1) summary
    cd07850
    Location:25 → 360
    STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

  5. XM_024994373.1 → XP_024850141.1  mitogen-activated protein kinase 9 isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:1 → 253
    PKc_like; Protein Kinases, catalytic domain

  6. XM_024994374.1 → XP_024850142.1  mitogen-activated protein kinase 9 isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:1 → 253
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein Strain
Heading Accession and Version

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