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PRKG2 protein kinase cGMP-dependent 2 [ Bos taurus (cattle) ]

Gene ID: 533330, updated on 4-Jul-2020

Summary

Official Symbol
PRKG2provided by VGNC
Official Full Name
protein kinase cGMP-dependent 2provided by VGNC
Primary source
VGNC:VGNC:33341
See related
BGD:BT19450; Ensembl:ENSBTAG00000002978
Gene type
protein coding
RefSeq status
INFERRED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

See PRKG2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
21
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 6 NC_037333.1 (95879148..96004142, complement)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 6 AC_000163.1 (97652569..97735627, complement)

Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 299 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene bone morphogenetic protein 3 Neighboring gene uncharacterized LOC112447106 Neighboring gene uncharacterized LOC112447107 Neighboring gene uncharacterized LOC112447167 Neighboring gene small nucleolar RNA SNORA70

Genomic regions, transcripts, and products

General gene information

Homology

General protein information

Preferred Names
cGMP-dependent protein kinase 2
Names
cGMP-dependant type II protein kinase
protein kinase, cGMP-dependent, type II
NP_001137571.1
XP_024849054.1
XP_024849055.1
XP_024849056.1
XP_024849057.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001144099.1NP_001137571.1  cGMP-dependent protein kinase 2

    See identical proteins and their annotated locations for NP_001137571.1

    Status: INFERRED

    Source sequence(s)
    AAFC03077638, AAFC03077640, AAFC03077642, AAFC03077643
    Conserved Domains (2) summary
    cd00038
    Location:286401
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    cd05572
    Location:459718
    STKc_cGK; Catalytic domain of the Serine/Threonine Kinase, cGMP-dependent protein kinase (cGK or PKG)

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037333.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    95879148..96004142 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024993287.1XP_024849055.1  cGMP-dependent protein kinase 2 isoform X1

    Conserved Domains (2) summary
    cd00038
    Location:286401
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    cd05572
    Location:459718
    STKc_cGK; Catalytic domain of the Serine/Threonine Kinase, cGMP-dependent protein kinase (cGK or PKG)
  2. XM_024993288.1XP_024849056.1  cGMP-dependent protein kinase 2 isoform X1

    Conserved Domains (2) summary
    cd00038
    Location:286401
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    cd05572
    Location:459718
    STKc_cGK; Catalytic domain of the Serine/Threonine Kinase, cGMP-dependent protein kinase (cGK or PKG)
  3. XM_024993286.1XP_024849054.1  cGMP-dependent protein kinase 2 isoform X1

    Related
    ENSBTAP00000003877.4, ENSBTAT00000003877.4
    Conserved Domains (2) summary
    cd00038
    Location:286401
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    cd05572
    Location:459718
    STKc_cGK; Catalytic domain of the Serine/Threonine Kinase, cGMP-dependent protein kinase (cGK or PKG)
  4. XM_024993289.1XP_024849057.1  cGMP-dependent protein kinase 2 isoform X2

    Conserved Domains (1) summary
    cd05572
    Location:1238
    STKc_cGK; Catalytic domain of the Serine/Threonine Kinase, cGMP-dependent protein kinase (cGK or PKG)
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