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MAP2K1 mitogen-activated protein kinase kinase 1 [ Bos taurus (domestic cattle) ]

Gene ID: 533199, updated on 5-Sep-2025
Official Symbol
MAP2K1provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase 1provided by VGNC
Primary source
VGNC:VGNC:31183
See related
BGD:BT26665; EnsemblRapid:ENSBTAG00070024624
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See MAP2K1 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (13276354..13351219)

Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene DIS3 like exosome 3'-5' exoribonuclease Neighboring gene small Cajal body-specific RNA 14 Neighboring gene TIMELESS interacting protein Neighboring gene small nuclear RNA activating complex polypeptide 5 Neighboring gene small nucleolar RNA SNORD18 Neighboring gene small nucleolar RNA SNORD18 Neighboring gene ribosomal protein L4

Genomic Sequence:
NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
dual specificity mitogen-activated protein kinase kinase 1
NP_001124224.1
XP_059746471.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130752.1 → NP_001124224.1  dual specificity mitogen-activated protein kinase kinase 1

    See identical proteins and their annotated locations for NP_001124224.1

    Status: PROVISIONAL

    Source sequence(s)
    BC119886
    UniProtKB/TrEMBL
    A0AAA9TUS2, F2Z4G4, Q0VD16
    Related
    ENSBTAP00070033650.1, ENSBTAT00070055977.1
    Conserved Domains (1) summary
    cd06650
    Location:62 → 380
    PKc_MEK1; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase 1

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    13276354..13351219
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059890488.1 → XP_059746471.1  dual specificity mitogen-activated protein kinase kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0AAA9S4V4, A0AAA9TUS2
    Related
    ENSBTAP00070033562.1, ENSBTAT00070055747.1
Nucleotide Protein Strain
Heading Accession and Version

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