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PLAGL2 PLAG1 like zinc finger 2 [ Homo sapiens (human) ]

Gene ID: 5326, updated on 13-Jan-2020

Summary

Official Symbol
PLAGL2provided by HGNC
Official Full Name
PLAG1 like zinc finger 2provided by HGNC
Primary source
HGNC:HGNC:9047
See related
Ensembl:ENSG00000126003 MIM:604866
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF900
Summary
Pleiomorphic adenoma gene-like 2 is a zinc-finger protein that recognizes DNA and/or RNA. [provided by RefSeq, Jul 2008]
Expression
Broad expression in bone marrow (RPKM 10.2), testis (RPKM 9.3) and 25 other tissues See more
Orthologs

Genomic context

See PLAGL2 in Genome Data Viewer
Location:
20q11.21
Exon count:
5
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 20 NC_000020.11 (32192504..32207743, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (30780307..30795546, complement)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene ribosomal L24 domain containing 1 pseudogene 6 Neighboring gene testis specific protein Y-linked 26, pseudogene Neighboring gene protein O-fucosyltransferase 1 Neighboring gene microRNA 1825 Neighboring gene kinesin family member 3B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23283

Gene Ontology Provided by GOA

Process Evidence Code Pubs
chylomicron assembly IEA
Inferred from Electronic Annotation
more info
 
lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of intrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
post-embryonic development IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein PLAGL2
Names
C2H2-type zinc finger protein
pleiomorphic adenoma gene-like 2
pleiomorphic adenoma-like protein 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_002657.3NP_002648.1  zinc finger protein PLAGL2

    See identical proteins and their annotated locations for NP_002648.1

    Status: REVIEWED

    Source sequence(s)
    AL121897, BC023655
    Consensus CDS
    CCDS13197.1
    UniProtKB/Swiss-Prot
    Q9UPG8
    Related
    ENSP00000246229.4, ENST00000246229.5
    Conserved Domains (2) summary
    sd00017
    Location:7092
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:85109
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p13 Primary Assembly

    Range
    32192504..32207743 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011528864.2XP_011527166.1  zinc finger protein PLAGL2 isoform X1

    See identical proteins and their annotated locations for XP_011527166.1

    UniProtKB/Swiss-Prot
    Q9UPG8
    Conserved Domains (2) summary
    sd00017
    Location:7092
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:85109
    zf-H2C2_2; Zinc-finger double domain
  2. XM_005260436.3XP_005260493.1  zinc finger protein PLAGL2 isoform X1

    See identical proteins and their annotated locations for XP_005260493.1

    UniProtKB/Swiss-Prot
    Q9UPG8
    Conserved Domains (2) summary
    sd00017
    Location:7092
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:85109
    zf-H2C2_2; Zinc-finger double domain
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