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PLAGL2 PLAG1 like zinc finger 2 [ Homo sapiens (human) ]

Gene ID: 5326, updated on 5-Aug-2022

Summary

Official Symbol
PLAGL2provided by HGNC
Official Full Name
PLAG1 like zinc finger 2provided by HGNC
Primary source
HGNC:HGNC:9047
See related
Ensembl:ENSG00000126003 MIM:604866; AllianceGenome:HGNC:9047
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF900
Summary
Pleiomorphic adenoma gene-like 2 is a zinc-finger protein that recognizes DNA and/or RNA. [provided by RefSeq, Jul 2008]
Expression
Broad expression in bone marrow (RPKM 10.2), testis (RPKM 9.3) and 25 other tissues See more
Orthologs
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Genomic context

See PLAGL2 in Genome Data Viewer
Location:
20q11.21
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (32192504..32207743, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (33916427..33931666, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (30780307..30795546, complement)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene ribosomal L24 domain containing 1 pseudogene 6 Neighboring gene testis specific protein Y-linked 26, pseudogene Neighboring gene protein O-fucosyltransferase 1 Neighboring gene uncharacterized LOC124904884 Neighboring gene microRNA 1825

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23283

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in chylomicron assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of intrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in post-embryonic development IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein PLAGL2
Names
C2H2-type zinc finger protein
pleiomorphic adenoma gene-like 2
pleiomorphic adenoma-like protein 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_002657.3NP_002648.1  zinc finger protein PLAGL2

    See identical proteins and their annotated locations for NP_002648.1

    Status: REVIEWED

    Source sequence(s)
    AL121897, BC023655
    Consensus CDS
    CCDS13197.1
    UniProtKB/Swiss-Prot
    Q92584, Q9UPG8
    Related
    ENSP00000246229.4, ENST00000246229.5
    Conserved Domains (2) summary
    sd00017
    Location:7092
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:85109
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    32192504..32207743 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047440200.1XP_047296156.1  zinc finger protein PLAGL2 isoform X1

    UniProtKB/Swiss-Prot
    Q92584
  2. XM_011528864.3XP_011527166.1  zinc finger protein PLAGL2 isoform X1

    See identical proteins and their annotated locations for XP_011527166.1

    UniProtKB/Swiss-Prot
    Q92584, Q9UPG8
    Conserved Domains (2) summary
    sd00017
    Location:7092
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:85109
    zf-H2C2_2; Zinc-finger double domain
  3. XM_005260436.4XP_005260493.1  zinc finger protein PLAGL2 isoform X1

    See identical proteins and their annotated locations for XP_005260493.1

    UniProtKB/Swiss-Prot
    Q92584, Q9UPG8
    Conserved Domains (2) summary
    sd00017
    Location:7092
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:85109
    zf-H2C2_2; Zinc-finger double domain

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    33916427..33931666 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)