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DGKI diacylglycerol kinase iota [ Bos taurus (cattle) ]

Gene ID: 530095, updated on 5-Mar-2024

Summary

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Official Symbol
DGKIprovided by VGNC
Official Full Name
diacylglycerol kinase iotaprovided by VGNC
Primary source
VGNC:VGNC:28030
See related
Ensembl:ENSBTAG00000019980
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (101053973..101568206, complement)

Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene cholinergic receptor muscarinic 2 Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene uncharacterized LOC112446425 Neighboring gene pleiotrophin Neighboring gene microRNA mir-12013 Neighboring gene cAMP responsive element binding protein 3 like 2 Neighboring gene aldo-keto reductase family 1 member D1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein kinase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of synaptic transmission, glutamatergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase iota
XP_010802895.2
XP_024846937.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    101053973..101568206 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010804593.4 → XP_010802895.2  diacylglycerol kinase iota isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LLJ7, F1N2W5
    Related
    ENSBTAP00000064917.2, ENSBTAT00000080144.2
    Conserved Domains (7) summary
    smart00045
    Location:471 → 628
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:323 → 444
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG1597
    Location:319 → 638
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    cd00204
    Location:870 → 984
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00130
    Location:196 → 255
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:867 → 962
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:895 → 928
    ANK; ANK repeat [structural motif]

  2. XM_024991169.2 → XP_024846937.1  diacylglycerol kinase iota isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LLJ7
    Conserved Domains (5) summary
    smart00045
    Location:407 → 564
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:259 → 380
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00204
    Location:806 → 920
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00130
    Location:132 → 191
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    sd00045
    Location:831 → 864
    ANK; ANK repeat [structural motif]
Nucleotide Protein Strain
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