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PMS1 PMS1 homolog 1, mismatch repair system component [ Bos taurus (cattle) ]

Gene ID: 529491, updated on 3-Jul-2020

Summary

Official Symbol
PMS1provided by VGNC
Official Full Name
PMS1 homolog 1, mismatch repair system componentprovided by VGNC
Primary source
VGNC:VGNC:33077
See related
Ensembl:ENSBTAG00000018795
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

See PMS1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 2 NC_037329.1 (6460095..6572063, complement)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 2 AC_000159.1 (6395004..6511175, complement)

Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene chromosome 2 C2orf88 homolog Neighboring gene protein kish-A pseudogene Neighboring gene myostatin Neighboring gene ORMDL sphingolipid biosynthesis regulator 1 Neighboring gene O-sialoglycoprotein endopeptidase like 1

Genomic regions, transcripts, and products

General gene information

Homology

Clone Names

  • MGC152061

General protein information

Preferred Names
PMS1 protein homolog 1
Names
PMS1 postmeiotic segregation increased 1
postmeiotic segregation 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077981.2NP_001071449.1  PMS1 protein homolog 1

    See identical proteins and their annotated locations for NP_001071449.1

    Status: PROVISIONAL

    Source sequence(s)
    BC126839
    UniProtKB/TrEMBL
    A0JNP9
    Related
    ENSBTAP00000025019.5, ENSBTAT00000025019.6
    Conserved Domains (5) summary
    COG5648
    Location:572724
    NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]
    cd01390
    Location:572636
    HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
    cd03485
    Location:205338
    MutL_Trans_hPMS_1_like; MutL_Trans_hPMS1_like: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to human PSM1 (hPSM1) and yeast MLH2. hPSM1 and yMLH2 are members of the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is ...
    TIGR00585
    Location:1318
    mutl; DNA mismatch repair protein MutL
    pfam02518
    Location:17144
    HATPase_c; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037329.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    6460095..6572063 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024975453.1XP_024831221.1  PMS1 protein homolog 1 isoform X2

    Conserved Domains (3) summary
    COG5648
    Location:511663
    NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]
    cd01390
    Location:511575
    HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...
    cl28386
    Location:1257
    MutL; DNA mismatch repair ATPase MutL [Replication, recombination and repair]
  2. XM_005202204.4XP_005202261.1  PMS1 protein homolog 1 isoform X1

    See identical proteins and their annotated locations for XP_005202261.1

    UniProtKB/TrEMBL
    F1MW63
    Conserved Domains (5) summary
    COG5648
    Location:572724
    NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]
    cd01390
    Location:572636
    HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
    cd03485
    Location:205338
    MutL_Trans_hPMS_1_like; MutL_Trans_hPMS1_like: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to human PSM1 (hPSM1) and yeast MLH2. hPSM1 and yMLH2 are members of the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is ...
    TIGR00585
    Location:1318
    mutl; DNA mismatch repair protein MutL
    pfam02518
    Location:17144
    HATPase_c; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
  3. XM_024975460.1XP_024831228.1  PMS1 protein homolog 1 isoform X3

    Conserved Domains (3) summary
    COG5648
    Location:397549
    NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]
    cd01390
    Location:397461
    HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...
    cd03485
    Location:30163
    MutL_Trans_hPMS_1_like; MutL_Trans_hPMS1_like: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to human PSM1 (hPSM1) and yeast MLH2. hPSM1 and yMLH2 are members of the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is ...

RNA

  1. XR_003029374.1 RNA Sequence

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