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Pnrc2 proline-rich nuclear receptor coactivator 2 [ Mus musculus (house mouse) ]

Gene ID: 52830, updated on 26-Sep-2022

Summary

Official Symbol
Pnrc2provided by MGI
Official Full Name
proline-rich nuclear receptor coactivator 2provided by MGI
Primary source
MGI:MGI:106512
See related
Ensembl:ENSMUSG00000028675 AllianceGenome:MGI:106512
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D4Bwg0593e; 0610011E17Rik
Summary
Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be active in P-body and nucleus. Is expressed in several structures, including brain ventricular layer; genitourinary system; retina; and thymus primordium. Orthologous to human PNRC2 (proline rich nuclear receptor coactivator 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 35.1), placenta adult (RPKM 28.9) and 26 other tissues See more
Orthologs
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Genomic context

See Pnrc2 in Genome Data Viewer
Location:
4 D3; 4 68.01 cM
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (135598229..135601157, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (135870917..135873846, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene myomesin family, member 3 Neighboring gene serine and arginine-rich splicing factor 10 Neighboring gene cannabinoid receptor 2 (macrophage) Neighboring gene fucosidase, alpha-L- 1, tissue

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC11707

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in P-body ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
proline-rich nuclear receptor coactivator 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026383.3NP_080659.1  proline-rich nuclear receptor coactivator 2

    See identical proteins and their annotated locations for NP_080659.1

    Status: VALIDATED

    Source sequence(s)
    AK011192, AK012073, AL672076
    Consensus CDS
    CCDS18792.1
    UniProtKB/Swiss-Prot
    Q9CR73, Q9CXC6
    Related
    ENSMUSP00000030436.6, ENSMUST00000030436.12
    Conserved Domains (1) summary
    pfam15365
    Location:94112
    PNRC; Proline-rich nuclear receptor coactivator motif

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    135598229..135601157 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006539038.2XP_006539101.1  proline-rich nuclear receptor coactivator 2 isoform X1

    See identical proteins and their annotated locations for XP_006539101.1

    UniProtKB/Swiss-Prot
    Q9CR73, Q9CXC6
    Conserved Domains (1) summary
    pfam15365
    Location:94112
    PNRC; Proline-rich nuclear receptor coactivator motif
  2. XM_006539039.2XP_006539102.1  proline-rich nuclear receptor coactivator 2 isoform X1

    See identical proteins and their annotated locations for XP_006539102.1

    UniProtKB/Swiss-Prot
    Q9CR73, Q9CXC6
    Conserved Domains (1) summary
    pfam15365
    Location:94112
    PNRC; Proline-rich nuclear receptor coactivator motif