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GPER1 G protein-coupled estrogen receptor 1 [ Bos taurus (domestic cattle) ]

Gene ID: 527831, updated on 30-Jan-2025
Official Symbol
GPER1provided by VGNC
Official Full Name
G protein-coupled estrogen receptor 1provided by VGNC
Primary source
VGNC:VGNC:29532
See related
EnsemblRapid:ENSBTAG00070014859
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
GPER
Orthologs
human mouse all
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See GPER1 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (41702578..41706359, complement)

Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112444286 Neighboring gene zinc finger AN1-type containing 2A Neighboring gene chromosome 25 C7orf50 homolog Neighboring gene G protein-coupled receptor 146 Neighboring gene microRNA mir-2389 Neighboring gene microRNA mir-339a

Genomic Sequence:
NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Cytoplasmic kinases downstream of GPR30 suppress gonadotropin-releasing hormone (GnRH)-induced luteinizing hormone secretion from bovine anterior pituitary cells. Rudolf FO, et al. J Reprod Dev, 2016. PMID 26522383, Free PMC Article
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PKA and MEK (thus, also pERK) are the intracellular mediators downstream of GPR30 that induce the non-genomic suppression of GnRH-induced LH secretion from bovine AP cells by estradiol or G1
    Title: Cytoplasmic kinases downstream of GPR30 suppress gonadotropin-releasing hormone (GnRH)-induced luteinizing hormone secretion from bovine anterior pituitary cells.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear estrogen receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to estradiol stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nuclear receptor-mediated steroid hormone signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
G-protein coupled estrogen receptor 1

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    41702578..41706359 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024985174.2 → XP_024840942.1  G-protein coupled estrogen receptor 1

    UniProtKB/TrEMBL
    A0AAA9TI99
    Related
    ENSBTAP00070019844.1, ENSBTAT00070033609.1
    Conserved Domains (2) summary
    cd14964
    Location:41 → 65
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:39 → 314
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
Nucleotide Protein Strain
Heading Accession and Version

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Molecular Biology Databases
Research Materials