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Echdc1 enoyl Coenzyme A hydratase domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 52665, updated on 26-Nov-2019

Summary

Official Symbol
Echdc1provided by MGI
Official Full Name
enoyl Coenzyme A hydratase domain containing 1provided by MGI
Primary source
MGI:MGI:1277169
See related
Ensembl:ENSMUSG00000019883
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MMCD; AI314462; AI930038; D10Ertd667e; 1700028A24Rik
Expression
Ubiquitous expression in bladder adult (RPKM 7.1), subcutaneous fat pad adult (RPKM 6.3) and 25 other tissues See more
Orthologs

Genomic context

See Echdc1 in Genome Data Viewer
Location:
10 A4; 10 16.59 cM
Exon count:
7
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (29298144..29346661)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (29032972..29066467)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene SOGA family member 3 Neighboring gene RIKEN cDNA 9330159F19 gene Neighboring gene predicted gene, 40620 Neighboring gene predicted gene, 46218 Neighboring gene ring finger protein 146 Neighboring gene predicted gene, 25596 Neighboring gene predicted gene, 30698

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
carboxy-lyase activity IDA
Inferred from Direct Assay
more info
PubMed 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enoyl-CoA hydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lyase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
fatty acid beta-oxidation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ethylmalonyl-CoA decarboxylase
Names
enoyl-CoA hydratase domain-containing protein 1
methylmalonyl-CoA decarboxylase
NP_001103665.1
NP_080131.4
XP_006512860.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110195.1NP_001103665.1  ethylmalonyl-CoA decarboxylase isoform b

    See identical proteins and their annotated locations for NP_001103665.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate 5' terminal exon and initiates translation at a downstream AUG start codon, compared to variant 1. The resulting isoform (b) has a shorter N-terminus, compared to isoform a.
    Source sequence(s)
    AK028775, AK150932, BY325699
    Consensus CDS
    CCDS48528.1
    UniProtKB/Swiss-Prot
    Q9D9V3
    Related
    ENSMUSP00000125553.1, ENSMUST00000160399.7
    Conserved Domains (1) summary
    cd06558
    Location:49243
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
  2. NM_025855.4NP_080131.4  ethylmalonyl-CoA decarboxylase isoform a

    See identical proteins and their annotated locations for NP_080131.4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a).
    Source sequence(s)
    AK006444, AK028775, CJ051963
    Consensus CDS
    CCDS23760.1
    UniProtKB/Swiss-Prot
    Q9D9V3
    Related
    ENSMUSP00000020034.4, ENSMUST00000020034.5
    Conserved Domains (1) summary
    cd06558
    Location:72266
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p6 C57BL/6J

    Range
    29298144..29346661
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512797.4XP_006512860.1  ethylmalonyl-CoA decarboxylase isoform X1

    Conserved Domains (1) summary
    cd06558
    Location:124318
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
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