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Adgra1 adhesion G protein-coupled receptor A1 [ Mus musculus (house mouse) ]

Gene ID: 52389, updated on 21-Apr-2024

Summary

Official Symbol
Adgra1provided by MGI
Official Full Name
adhesion G protein-coupled receptor A1provided by MGI
Primary source
MGI:MGI:1277167
See related
Ensembl:ENSMUSG00000025475 AllianceGenome:MGI:1277167
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gpr123; D7Ertd680e; 2900059M17Rik
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in cell surface receptor signaling pathway. Located in glutamatergic synapse and postsynaptic density. Is expressed in several structures, including adrenal gland; central nervous system; eye; and genitourinary system. Orthologous to human ADGRA1 (adhesion G protein-coupled receptor A1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cortex adult (RPKM 8.4), frontal lobe adult (RPKM 7.5) and 8 other tissues See more
Orthologs
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Genomic context

Location:
7 F4; 7 84.89 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (139414014..139458004)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (139834097..139878088)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L24 pseudogene Neighboring gene microRNA 6401 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene kinase non-catalytic C-lobe domain (KIND) containing 1 Neighboring gene STARR-seq mESC enhancer starr_20433

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in glutamatergic synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in glutamatergic synapse IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in postsynaptic density EXP
Inferred from Experiment
more info
PubMed 
is_active_in postsynaptic density IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
adhesion G protein-coupled receptor A1
Names
G protein coupled receptor Gpr123
G protein-coupled receptor 123
probable G-protein coupled receptor 123

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177469.3NP_803420.2  adhesion G protein-coupled receptor A1

    See identical proteins and their annotated locations for NP_803420.2

    Status: VALIDATED

    Source sequence(s)
    AK082207, BC056493, BE651866, BG083237
    Consensus CDS
    CCDS40171.1
    UniProtKB/Swiss-Prot
    Q8C4G9, Q8CC05
    UniProtKB/TrEMBL
    Q76JQ1
    Related
    ENSMUSP00000026548.8, ENSMUST00000026548.14
    Conserved Domains (1) summary
    cl21561
    Location:29299
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    139414014..139458004
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006536203.5XP_006536266.1  adhesion G protein-coupled receptor A1 isoform X1

    See identical proteins and their annotated locations for XP_006536266.1

    UniProtKB/TrEMBL
    Q76JQ1
    Conserved Domains (2) summary
    cd14964
    Location:1741
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:14325
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily