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CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 [ Bos taurus (domestic cattle) ]

Gene ID: 523793, updated on 5-Sep-2025
Official Symbol
CELSR3provided by VGNC
Official Full Name
cadherin EGF LAG seven-pass G-type receptor 3provided by VGNC
Primary source
VGNC:VGNC:27171
See related
EnsemblRapid:ENSBTAG00070029966
Gene type
protein coding
RefSeq status
INFERRED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See CELSR3 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
35
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (51220718..51248173)

Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene inositol hexakisphosphate kinase 2 Neighboring gene NCK interacting protein with SH3 domain Neighboring gene solute carrier family 26 member 6 Neighboring gene transmembrane protein 89

Genomic Sequence:
NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
cadherin EGF LAG seven-pass G-type receptor 3
Names
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
NP_001192266.2

Length

  • 3314

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001205337.2 → NP_001192266.2  cadherin EGF LAG seven-pass G-type receptor 3 precursor

    Status: INFERRED

    Source sequence(s)
    DAAA02054431
    UniProtKB/TrEMBL
    F1MHH5
    Related
    ENSBTAP00070041512.1, ENSBTAT00070067971.1
    Conserved Domains (11) summary
    smart00303
    Location:2477 → 2530
    GPS; G-protein-coupled receptor proteolytic site domain
    cd11304
    Location:653 → 750
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00008
    Location:2124 → 2182
    HormR; Domain present in hormone receptors
    cd00054
    Location:1435 → 1469
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:2074 → 2112
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:1515 → 1698
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00053
    Location:2001 → 2040
    Laminin_EGF; Laminin EGF domain
    pfam16489
    Location:2202 → 2451
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd15993
    Location:2540 → 2564
    7tmB2_CELSR3; TM helix 1 [structural motif]
    cl28033
    Location:3087 → 3312
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
    cl28897
    Location:2537 → 2789
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    51220718..51248173
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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Research Materials