U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Atxn1l ataxin 1-like [ Mus musculus (house mouse) ]

Gene ID: 52335, updated on 12-May-2024

Summary

Official Symbol
Atxn1lprovided by MGI
Official Full Name
ataxin 1-likeprovided by MGI
Primary source
MGI:MGI:3694797
See related
Ensembl:ENSMUSG00000069895 AllianceGenome:MGI:3694797
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Boat; D6Mgi37; D8Ertd587e; C330011L24Rik
Summary
Predicted to enable DNA binding activity and RNA binding activity. Involved in brain development; learning or memory; and social behavior. Acts upstream of or within several processes, including lung alveolus development; negative regulation of transcription by RNA polymerase II; and positive regulation of hematopoietic stem cell proliferation. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in nucleus. Orthologous to human ATXN1L (ataxin 1 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 14.3), lung adult (RPKM 9.6) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Atxn1l in Genome Data Viewer
Location:
8 D3; 8 57.22 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (110453083..110464426, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (109726451..109737794, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene polycystic kidney disease 1 like 3 Neighboring gene STARR-positive B cell enhancer ABC_E3805 Neighboring gene increased sodium tolerance 1 homolog (yeast) Neighboring gene zinc finger protein 821 Neighboring gene predicted gene, 53453 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:112261750-112261859 Neighboring gene STARR-seq mESC enhancer starr_22658 Neighboring gene STARR-seq mESC enhancer starr_22659 Neighboring gene STARR-seq mESC enhancer starr_22660 Neighboring gene predicted gene, 51550 Neighboring gene La ribonucleoprotein domain family, member 1B pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:112302310-112302493 Neighboring gene STARR-seq mESC enhancer starr_22661 Neighboring gene adaptor protein complex AP-1, gamma 1 subunit Neighboring gene predicted gene, 17344 Neighboring gene small nucleolar RNA, C/D box 71

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (3)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables POZ domain binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ataxin-1-like
Names
brother of ataxin-1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080930.2NP_001074399.1  ataxin-1-like

    See identical proteins and their annotated locations for NP_001074399.1

    Status: VALIDATED

    Source sequence(s)
    AC132138
    Consensus CDS
    CCDS40474.1
    UniProtKB/Swiss-Prot
    P0C7T6
    Related
    ENSMUSP00000090850.4, ENSMUST00000093162.4
    Conserved Domains (2) summary
    PTZ00395
    Location:111302
    PTZ00395; Sec24-related protein; Provisional
    pfam08517
    Location:467578
    AXH; Ataxin-1 and HBP1 module (AXH)
  2. NM_001368350.1NP_001355279.1  ataxin-1-like

    Status: VALIDATED

    Source sequence(s)
    AC132138
    Consensus CDS
    CCDS40474.1
    UniProtKB/Swiss-Prot
    P0C7T6
    Conserved Domains (2) summary
    PTZ00395
    Location:111302
    PTZ00395; Sec24-related protein; Provisional
    pfam08517
    Location:467578
    AXH; Ataxin-1 and HBP1 module (AXH)
  3. NM_001368351.1NP_001355280.1  ataxin-1-like

    Status: VALIDATED

    Source sequence(s)
    AC132138
    Consensus CDS
    CCDS40474.1
    UniProtKB/Swiss-Prot
    P0C7T6
    Related
    ENSMUSP00000148324.2, ENSMUST00000212605.2
    Conserved Domains (2) summary
    PTZ00395
    Location:111302
    PTZ00395; Sec24-related protein; Provisional
    pfam08517
    Location:467578
    AXH; Ataxin-1 and HBP1 module (AXH)
  4. NM_001368352.1NP_001355281.1  ataxin-1-like

    Status: VALIDATED

    Source sequence(s)
    AC132138
    Consensus CDS
    CCDS40474.1
    UniProtKB/Swiss-Prot
    P0C7T6
    Conserved Domains (2) summary
    PTZ00395
    Location:111302
    PTZ00395; Sec24-related protein; Provisional
    pfam08517
    Location:467578
    AXH; Ataxin-1 and HBP1 module (AXH)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    110453083..110464426 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248439.3XP_011246741.1  ataxin-1-like isoform X1

    See identical proteins and their annotated locations for XP_011246741.1

    UniProtKB/Swiss-Prot
    P0C7T6
    Conserved Domains (2) summary
    PTZ00395
    Location:111302
    PTZ00395; Sec24-related protein; Provisional
    pfam08517
    Location:467578
    AXH; Ataxin-1 and HBP1 module (AXH)
  2. XM_030243670.2XP_030099530.1  ataxin-1-like isoform X1

    UniProtKB/Swiss-Prot
    P0C7T6
    Conserved Domains (2) summary
    PTZ00395
    Location:111302
    PTZ00395; Sec24-related protein; Provisional
    pfam08517
    Location:467578
    AXH; Ataxin-1 and HBP1 module (AXH)