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Commd2 COMM domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 52245, updated on 5-Mar-2024

Summary

Official Symbol
Commd2provided by MGI
Official Full Name
COMM domain containing 2provided by MGI
Primary source
MGI:MGI:1098806
See related
Ensembl:ENSMUSG00000036513 AllianceGenome:MGI:1098806
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
HSPC042; D3Ertd176e; 1190017G07Rik
Summary
Predicted to be located in cytoplasm. Orthologous to human COMMD2 (COMM domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E14 (RPKM 6.7), CNS E11.5 (RPKM 6.7) and 28 other tissues See more
Orthologs
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Genomic context

See Commd2 in Genome Data Viewer
Location:
3 D; 3 27.94 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (57551770..57559105, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (57644349..57651684, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene WW domain containing transcription regulator 1 Neighboring gene NEDD8-conjugating enzyme UBE2F pseudogene Neighboring gene STARR-seq mESC enhancer starr_07733 Neighboring gene STARR-seq mESC enhancer starr_07736 Neighboring gene predicted gene, 26671 Neighboring gene microRNA 6377 Neighboring gene predicted gene, 46805 Neighboring gene STARR-positive B cell enhancer ABC_E7913 Neighboring gene STARR-seq mESC enhancer starr_07737 Neighboring gene ankyrin repeat and ubiquitin domain containing 1 Neighboring gene ribosomal protein S11 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
COMM domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175095.4NP_780304.2  COMM domain-containing protein 2

    See identical proteins and their annotated locations for NP_780304.2

    Status: PROVISIONAL

    Source sequence(s)
    AK143821
    Consensus CDS
    CCDS17362.1
    UniProtKB/Swiss-Prot
    Q8BJI3, Q8BXC6
    UniProtKB/TrEMBL
    Q497T6
    Related
    ENSMUSP00000124819.2, ENSMUST00000160959.8
    Conserved Domains (1) summary
    cd04750
    Location:26190
    Commd2; COMM_Domain containing protein 2. The COMM Domain is found at the C-terminus of a variety of proteins; presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    57551770..57559105 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)