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GRAP2 GRB2 related adaptor protein 2 [ Bos taurus (domestic cattle) ]

Gene ID: 522346, updated on 30-Jan-2025
Official Symbol
GRAP2provided by VGNC
Official Full Name
GRB2 related adaptor protein 2provided by VGNC
Primary source
VGNC:VGNC:29627
See related
BGD:BT25427; EnsemblRapid:ENSBTAG00070028991
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See GRAP2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (111263107..111330676)

Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene calcium voltage-gated channel subunit alpha1 I Neighboring gene ENTH domain containing 1 Neighboring gene family with sequence similarity 83 member F Neighboring gene uncharacterized LOC132345362

Genomic Sequence:
NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
GRB2-related adapter protein 2

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001192560.1 → NP_001179489.1  GRB2-related adapter protein 2

    See identical proteins and their annotated locations for NP_001179489.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000005
    UniProtKB/TrEMBL
    E1BKA6
    Related
    ENSBTAP00070039948.1, ENSBTAT00070065872.1
    Conserved Domains (3) summary
    cd09941
    Location:54 → 147
    SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
    cd11950
    Location:261 → 313
    SH3_GRAP2_C; C-terminal Src homology 3 domain of GRB2-related adaptor protein 2
    cl17036
    Location:2 → 53
    SH3; Src Homology 3 domain superfamily

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    111263107..111330676
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005207393.5 → XP_005207450.1  GRB2-related adapter protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005207450.1

    UniProtKB/TrEMBL
    E1BKA6
    Conserved Domains (3) summary
    cd09941
    Location:54 → 147
    SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
    cd11950
    Location:261 → 313
    SH3_GRAP2_C; C-terminal Src homology 3 domain of GRB2-related adaptor protein 2
    cl17036
    Location:2 → 53
    SH3; Src Homology 3 domain superfamily

  2. XM_005207394.5 → XP_005207451.1  GRB2-related adapter protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005207451.1

    UniProtKB/TrEMBL
    E1BKA6
    Conserved Domains (3) summary
    cd09941
    Location:54 → 147
    SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
    cd11950
    Location:261 → 313
    SH3_GRAP2_C; C-terminal Src homology 3 domain of GRB2-related adaptor protein 2
    cl17036
    Location:2 → 53
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein Strain
Heading Accession and Version

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