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IL6ST interleukin 6 cytokine family signal transducer [ Bos taurus (domestic cattle) ]

Gene ID: 522155, updated on 30-Jan-2025
Official Symbol
IL6STprovided by VGNC
Official Full Name
interleukin 6 cytokine family signal transducerprovided by VGNC
Primary source
VGNC:VGNC:30168
See related
EnsemblRapid:ENSBTAG00070020210
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See IL6ST in Genome Data Viewer
Location:
chromosome: 20
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 20 NC_037347.1 (23191788..23253568)

Chromosome 20 - NC_037347.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112442996 Neighboring gene ankyrin repeat domain 55 Neighboring gene uncharacterized LOC101905381 Neighboring gene microRNA mir-2359 Neighboring gene GTP-binding nuclear protein Ran-like Neighboring gene interleukin 31 receptor A Neighboring gene DEAD-box helicase 4

Genomic Sequence:
NC_037347.1 Chromosome 20 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables interleukin-6 binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-6 receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
interleukin-6 receptor subunit beta
Names
interleukin 6 signal transducer (gp130, oncostatin M receptor)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037347.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    23191788..23253568
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002696322.7 → XP_002696368.3  interleukin-6 receptor subunit beta isoform X2

    See identical proteins and their annotated locations for XP_002696368.3

    UniProtKB/TrEMBL
    A0AAA9SYA1, E1BD36
    Related
    ENSBTAP00070027423.1, ENSBTAT00070045750.1
    Conserved Domains (4) summary
    smart00060
    Location:519 → 599
    FN3; Fibronectin type 3 domain
    cd00063
    Location:223 → 321
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam06328
    Location:27 → 111
    Lep_receptor_Ig; Ig-like C2-type domain
    cl21522
    Location:121 → 215
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  2. XM_059878870.1 → XP_059734853.1  interleukin-6 receptor subunit beta isoform X3

    UniProtKB/TrEMBL
    A0AAA9SYA1
    Related
    ENSBTAP00070027435.1, ENSBTAT00070045780.1

  3. XM_010816769.4 → XP_010815071.2  interleukin-6 receptor subunit beta isoform X1

    UniProtKB/TrEMBL
    A0AAA9SYA1
Nucleotide Protein Strain
Heading Accession and Version

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