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Anapc4 anaphase promoting complex subunit 4 [ Mus musculus (house mouse) ]

Gene ID: 52206, updated on 9-Sep-2018

Summary

Official Symbol
Anapc4provided by MGI
Official Full Name
anaphase promoting complex subunit 4provided by MGI
Primary source
MGI:MGI:1098673
See related
Ensembl:ENSMUSG00000029176 Vega:OTTMUSG00000023353
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
APC4; D5Ertd249e; 2610306D21Rik
Expression
Broad expression in CNS E11.5 (RPKM 38.1), CNS E14 (RPKM 29.2) and 24 other tissues See more
Orthologs

Genomic context

See Anapc4 in Genome Data Viewer
Location:
5 C1; 5 28.81 cM
Exon count:
28
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (52834135..52866734)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (53225374..53257973)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol 4-kinase type 2 beta Neighboring gene zinc finger, CCHC domain containing 4 Neighboring gene predicted gene, 30241 Neighboring gene RIKEN cDNA 5033403H07 gene Neighboring gene predicted gene, 30301

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein phosphatase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein phosphatase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
anaphase-promoting complex-dependent catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
positive regulation of mitotic metaphase/anaphase transition IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein K11-linked ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein K11-linked ubiquitination ISO
Inferred from Sequence Orthology
more info
 
regulation of mitotic metaphase/anaphase transition IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
anaphase-promoting complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
anaphase-promoting complex ISO
Inferred from Sequence Orthology
more info
 
nuclear periphery IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
anaphase-promoting complex subunit 4
Names
cyclosome subunit 4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024213.2NP_077175.1  anaphase-promoting complex subunit 4

    See identical proteins and their annotated locations for NP_077175.1

    Status: PROVISIONAL

    Source sequence(s)
    AC102766
    Consensus CDS
    CCDS19290.1
    UniProtKB/Swiss-Prot
    Q91W96
    UniProtKB/TrEMBL
    Q3TM92
    Related
    ENSMUSP00000031072.7, OTTMUSP00000027238, ENSMUST00000031072.13, OTTMUST00000056627
    Conserved Domains (4) summary
    pfam12894
    Location:1057
    ANAPC4_WD40; Anaphase-promoting complex subunit 4 WD40 domain
    pfam12896
    Location:232431
    ANAPC4; Anaphase-promoting complex, cyclosome, subunit 4
    sd00039
    Location:2459
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:26115
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

    Range
    52834135..52866734
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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