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AASS aminoadipate-semialdehyde synthase [ Bos taurus (cattle) ]

Gene ID: 520865, updated on 22-Jan-2019

Summary

Official Symbol
AASSprovided by VGNC
Official Full Name
aminoadipate-semialdehyde synthaseprovided by VGNC
Primary source
VGNC:VGNC:25451
See related
BGD:BT18318; Ensembl:ENSBTAG00000012128
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs

Genomic context

See AASS in Genome Data Viewer
Location:
chromosome: 4
Exon count:
25
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 4 NC_037331.1 (86512542..86594714, complement)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 4 AC_000161.1 (87301469..87373279, complement)

Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein SA pseudogene Neighboring gene protein tyrosine phosphatase, receptor type Z1 Neighboring gene 40S ribosomal protein S2 pseudogene Neighboring gene chromobox protein homolog 3 pseudogene

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Clone Names

  • MGC166100

Gene Ontology Provided by GOA

Function Evidence Code Pubs
saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity IEA
Inferred from Electronic Annotation
more info
 
saccharopine dehydrogenase (NADP+, L-lysine-forming) activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
L-lysine catabolic process to acetyl-CoA via saccharopine IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
alpha-aminoadipic semialdehyde synthase, mitochondrial
Names
LKR/SDH
NP_001103267.1
XP_024846465.1
XP_024846466.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109797.1NP_001103267.1  alpha-aminoadipic semialdehyde synthase, mitochondrial precursor

    See identical proteins and their annotated locations for NP_001103267.1

    Status: PROVISIONAL

    Source sequence(s)
    BC153851
    UniProtKB/Swiss-Prot
    A8E657
    Related
    ENSBTAP00000016090.6, ENSBTAT00000016090.6
    Conserved Domains (2) summary
    cd12189
    Location:25466
    LKR_SDH_like; bifunctional lysine ketoglutarate reductase /saccharopine dehydrogenase enzyme
    cl25613
    Location:25916
    Sacchrp_dh_C; Saccharopine dehydrogenase C-terminal domain

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037331.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    86512542..86594714 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024990698.1XP_024846466.1  alpha-aminoadipic semialdehyde synthase, mitochondrial isoform X2

    Related
    ENSBTAP00000058471.1, ENSBTAT00000080443.1
    Conserved Domains (2) summary
    cd12189
    Location:25466
    LKR_SDH_like; bifunctional lysine ketoglutarate reductase /saccharopine dehydrogenase enzyme
    cl25613
    Location:25916
    Sacchrp_dh_C; Saccharopine dehydrogenase C-terminal domain
  2. XM_024990697.1XP_024846465.1  alpha-aminoadipic semialdehyde synthase, mitochondrial isoform X1

    Conserved Domains (2) summary
    cd12189
    Location:31472
    LKR_SDH_like; bifunctional lysine ketoglutarate reductase /saccharopine dehydrogenase enzyme
    cl25613
    Location:31922
    Sacchrp_dh_C; Saccharopine dehydrogenase C-terminal domain
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