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Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit [ Mus musculus (house mouse) ]

Gene ID: 52014, updated on 23-Jun-2021

Summary

Official Symbol
Nus1provided by MGI
Official Full Name
NUS1 dehydrodolichyl diphosphate synthase subunitprovided by MGI
Primary source
MGI:MGI:1196365
See related
Ensembl:ENSMUSG00000023068
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ng; AU019165; AW538011; BC003223; D10Ertd438; D10Ertd438e; 1600027K07Rik
Expression
Ubiquitous expression in kidney adult (RPKM 26.3), adrenal adult (RPKM 18.5) and 28 other tissues See more
Orthologs
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Genomic context

See Nus1 in Genome Data Viewer
Location:
10 B3; 10 26.64 cM
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (52293643..52316288)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (52417547..52440192)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (52137353..52159998)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S19, pseudogene 10 Neighboring gene nephrocan Neighboring gene predicted gene, 47612 Neighboring gene zinc finger protein, autosomal, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC7199

Gene Ontology Provided by MGI

Function Evidence Code Pubs
contributes_to dehydrodolichyl diphosphate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables dehydrodolichyl diphosphate synthase activity ISO
Inferred from Sequence Orthology
more info
 
enables prenyltransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
contributes_to prenyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity, transferring alkyl or aryl (other than methyl) groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within angiogenesis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cholesterol homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in dolichol biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within dolichol biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in dolichyl diphosphate biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of blood vessel endothelial cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of nitric-oxide synthase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in protein glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within protein mannosylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of intracellular cholesterol transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of intracellular cholesterol transport ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within sterol homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vascular endothelial growth factor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of dehydrodolichyl diphosphate synthase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of dehydrodolichyl diphosphate synthase complex ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
dehydrodolichyl diphosphate synthase complex subunit Nus1
Names
Nogo-B receptor
dehydrodolichyl diphosphate syntase complex subunit Nus1
di-trans,poly-cis-decaprenylcistransferase
ngBR
nuclear undecaprenyl pyrophosphate synthase 1 homolog
NP_084526.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030250.2NP_084526.1  dehydrodolichyl diphosphate synthase complex subunit Nus1

    See identical proteins and their annotated locations for NP_084526.1

    Status: VALIDATED

    Source sequence(s)
    AC153526
    Consensus CDS
    CCDS23841.1
    UniProtKB/Swiss-Prot
    Q99LJ8
    Related
    ENSMUSP00000023830.9, ENSMUST00000023830.16
    Conserved Domains (1) summary
    COG0020
    Location:124297
    UppS; Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    52293643..52316288
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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