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LAMB1 laminin subunit beta 1 [ Bos taurus (domestic cattle) ]

Gene ID: 520030, updated on 4-Feb-2026
Official Symbol
LAMB1provided by VGNC
Official Full Name
laminin subunit beta 1provided by VGNC
Primary source
VGNC:VGNC:30772
See related
EnsemblRapid:ENSBTAG00070024107
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
all
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See LAMB1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (48985684..49062382, complement)

Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene uncharacterized LOC132345088 Neighboring gene dihydrolipoamide dehydrogenase Neighboring gene microRNA mir-2418 Neighboring gene uncharacterized LOC132345089 Neighboring gene neuronal cell adhesion molecule

Genomic Sequence:
NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Alterations in gene expression associated with changes in the state of endothelial differentiation. Shima DT, et al. Differentiation, 1995 Feb. PMID 7713329
  2. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in animal organ morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in basement membrane assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in substrate adhesion-dependent cell spreading IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tissue development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of laminin trimer IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
laminin subunit beta-1
Names
laminin, beta 1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001206519.1 → NP_001193448.1  laminin subunit beta-1 precursor

    Status: VALIDATED

    Source sequence(s)
    CK849175, DN532436, DV816626, DV918665, EE364652, EE374088, EE377103, EH179945, EW680861, NKLS02000004
    UniProtKB/TrEMBL
    F1MNT4
    Related
    ENSBTAP00070032547.1, ENSBTAT00070054318.1
    Conserved Domains (8) summary
    smart00180
    Location:773 → 818
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1340
    Location:1449 → 1778
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00055
    Location:509 → 548
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:821 → 869
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:44 → 269
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam01442
    Location:1190 → 1386
    Apolipoprotein; Apolipoprotein A1/A4/E domain
    pfam15704
    Location:1472 → 1688
    Mt_ATP_synt; Mitochondrial ATP synthase subunit
    cl09111
    Location:1649 → 1757
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    48985684..49062382 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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Molecular Biology Databases
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