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TM7SF3 transmembrane 7 superfamily member 3 [ Homo sapiens (human) ]

Gene ID: 51768, updated on 4-Jul-2021

Summary

Official Symbol
TM7SF3provided by HGNC
Official Full Name
transmembrane 7 superfamily member 3provided by HGNC
Primary source
HGNC:HGNC:23049
See related
Ensembl:ENSG00000064115 MIM:605181
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in kidney (RPKM 20.0), lung (RPKM 8.4) and 25 other tissues See more
Orthologs
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Genomic context

See TM7SF3 in Genome Data Viewer
Location:
12p11.23
Exon count:
13
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (26966524..27014427, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (27124512..27167317, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene inositol 1,4,5-trisphosphate receptor type 2 Neighboring gene uncharacterized LOC105369706 Neighboring gene enoyl-CoA hydratase domain containing 2 pseudogene Neighboring gene integrator complex subunit 13 Neighboring gene FGFR1 oncogene partner 2 Neighboring gene mediator complex subunit 21 Neighboring gene chromosome 12 open reading frame 71

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in extracellular exosome HDA PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
transmembrane 7 superfamily member 3
Names
seven span transmembrane protein
seven transmembrane protein TM7SF3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016551.3NP_057635.1  transmembrane 7 superfamily member 3 precursor

    See identical proteins and their annotated locations for NP_057635.1

    Status: VALIDATED

    Source sequence(s)
    AC024896, BC005176, DA719107
    Consensus CDS
    CCDS8710.1
    UniProtKB/Swiss-Prot
    Q9NS93
    Related
    ENSP00000342322.4, ENST00000343028.9
    Conserved Domains (1) summary
    pfam13886
    Location:296503
    DUF4203; Domain of unknown function (DUF4203)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    26966524..27014427 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017019463.2XP_016874952.1  transmembrane 7 superfamily member 3 isoform X1

  2. XM_011520690.3XP_011518992.1  transmembrane 7 superfamily member 3 isoform X4

    Conserved Domains (1) summary
    pfam13886
    Location:174381
    DUF4203; Domain of unknown function (DUF4203)
  3. XM_017019466.2XP_016874955.1  transmembrane 7 superfamily member 3 isoform X6

  4. XM_005253391.4XP_005253448.1  transmembrane 7 superfamily member 3 isoform X2

    Conserved Domains (1) summary
    pfam13886
    Location:296452
    DUF4203; Domain of unknown function (DUF4203)
  5. XM_017019465.2XP_016874954.1  transmembrane 7 superfamily member 3 isoform X5

  6. XM_017019464.2XP_016874953.1  transmembrane 7 superfamily member 3 isoform X3

  7. XM_011520691.2XP_011518993.1  transmembrane 7 superfamily member 3 isoform X7

RNA

  1. XR_002957337.1 RNA Sequence

  2. XR_001748764.2 RNA Sequence

  3. XR_001748762.2 RNA Sequence

  4. XR_001748763.2 RNA Sequence

  5. XR_931305.3 RNA Sequence

  6. XR_242895.4 RNA Sequence

  7. XR_931304.3 RNA Sequence

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