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JAG2 jagged canonical Notch ligand 2 [ Bos taurus (domestic cattle) ]

Gene ID: 517405, updated on 30-Jan-2025
Official Symbol
JAG2provided by VGNC
Official Full Name
jagged canonical Notch ligand 2provided by VGNC
Primary source
VGNC:VGNC:30362
See related
EnsemblRapid:ENSBTAG00070017181
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See JAG2 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 21 NC_037348.1 (69505929..69527022, complement)

Chromosome 21 - NC_037348.1Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 132 Neighboring gene large ribosomal subunit protein uL11-like Neighboring gene nudix hydrolase 14 Neighboring gene BRF1 RNA polymerase III transcription initiation factor subunit Neighboring gene BTB domain containing 6

Genomic Sequence:
NC_037348.1 Chromosome 21 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Notch binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell communication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
protein jagged-2
Names
jagged 2

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037348.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    69505929..69527022 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024982221.2 → XP_024837989.1  protein jagged-2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1M9Y8, A0A3Q1MGT9
    Related
    ENSBTAP00070022939.1, ENSBTAT00070038697.1
    Conserved Domains (5) summary
    smart00215
    Location:833 → 904
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:307 → 345
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00008
    Location:351 → 381
    EGF; EGF-like domain
    pfam01414
    Location:178 → 240
    DSL; Delta serrate ligand
    pfam07657
    Location:28 → 103
    MNNL; N terminus of Notch ligand

  2. XM_024982220.2 → XP_024837988.1  protein jagged-2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1M9Y8, G3X6N5
    Related
    ENSBTAP00070022937.1, ENSBTAT00070038692.1
    Conserved Domains (5) summary
    smart00215
    Location:871 → 942
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:307 → 345
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00008
    Location:351 → 381
    EGF; EGF-like domain
    pfam01414
    Location:178 → 240
    DSL; Delta serrate ligand
    pfam07657
    Location:28 → 103
    MNNL; N terminus of Notch ligand
Nucleotide Protein Strain
Heading Accession and Version

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