Format

Send to:

Choose Destination

CAB39 calcium binding protein 39 [ Homo sapiens (human) ]

Gene ID: 51719, updated on 1-Jun-2020

Summary

Official Symbol
CAB39provided by HGNC
Official Full Name
calcium binding protein 39provided by HGNC
Primary source
HGNC:HGNC:20292
See related
Ensembl:ENSG00000135932 MIM:612174
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MO25; CGI-66
Expression
Ubiquitous expression in colon (RPKM 18.8), appendix (RPKM 18.4) and 25 other tissues See more
Orthologs

Genomic context

See CAB39 in Genome Data Viewer
Location:
2q37.1
Exon count:
11
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (230712842..230821075)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (231577557..231685790)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr2.6880 Neighboring gene long intergenic non-protein coding RNA 1907 Neighboring gene BANF1 pseudogene 3 Neighboring gene RNA, U6 small nuclear 268, pseudogene Neighboring gene integral membrane protein 2C Neighboring gene GPR55 cis regulatory suppressor of immune response RNA

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ22682

Gene Ontology Provided by GOA

Function Evidence Code Pubs
kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase activator activity IDA
Inferred from Direct Assay
more info
PubMed 
protein serine/threonine kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine kinase activator activity IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein-containing complex binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Z disc IEA
Inferred from Electronic Annotation
more info
 
cytosol TAS
Traceable Author Statement
more info
 
extracellular exosome HDA PubMed 
extracellular region TAS
Traceable Author Statement
more info
 
ficolin-1-rich granule lumen TAS
Traceable Author Statement
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
secretory granule lumen TAS
Traceable Author Statement
more info
 
serine/threonine protein kinase complex IC
Inferred by Curator
more info
PubMed 

General protein information

Preferred Names
calcium-binding protein 39
Names
MO25alpha

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130849.1NP_001124321.1  calcium-binding protein 39

    See identical proteins and their annotated locations for NP_001124321.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents an alternate non-coding exon in the 5'UTR compared to variant 1. The same protein is encoded by variants 1, 2, and 3.
    Source sequence(s)
    AF113536, AK000804, AK292382
    Consensus CDS
    CCDS2478.1
    UniProtKB/Swiss-Prot
    Q9Y376
    UniProtKB/TrEMBL
    A0A024R496
    Related
    ENSP00000386238.3, ENST00000409788.7
    Conserved Domains (1) summary
    pfam08569
    Location:54325
    Mo25; Mo25-like
  2. NM_001130850.1NP_001124322.1  calcium-binding protein 39

    See identical proteins and their annotated locations for NP_001124322.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents an alternate non-coding exon in the 5'UTR compared to variant 1. The same protein is encoded by variants 1, 2, and 3.
    Source sequence(s)
    AC084031, AF113536, AK000804, AK315692, DB455871
    Consensus CDS
    CCDS2478.1
    UniProtKB/Swiss-Prot
    Q9Y376
    UniProtKB/TrEMBL
    A0A024R496
    Related
    ENSP00000386642.3, ENST00000410084.7
    Conserved Domains (1) summary
    pfam08569
    Location:54325
    Mo25; Mo25-like
  3. NM_016289.4NP_057373.1  calcium-binding protein 39

    See identical proteins and their annotated locations for NP_057373.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents an alternate non-coding exon in the 5'UTR. The same protein is encoded by variants 1, 2, and 3.
    Source sequence(s)
    AF113536, AK000804, BC020570, BG773506, DA886579
    Consensus CDS
    CCDS2478.1
    UniProtKB/Swiss-Prot
    Q9Y376
    UniProtKB/TrEMBL
    A0A024R496
    Related
    ENSP00000258418.5, ENST00000258418.10
    Conserved Domains (1) summary
    pfam08569
    Location:54325
    Mo25; Mo25-like

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    230712842..230821075
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011511350.2XP_011509652.1  calcium-binding protein 39 isoform X1

    Conserved Domains (1) summary
    pfam08569
    Location:5209
    Mo25; Mo25-like
Support Center