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ACP5 acid phosphatase 5, tartrate resistant [ Bos taurus (domestic cattle) ]

Gene ID: 517002, updated on 5-Sep-2025
Official Symbol
ACP5provided by VGNC
Official Full Name
acid phosphatase 5, tartrate resistantprovided by VGNC
Primary source
VGNC:VGNC:25556
See related
BGD:BT10988; EnsemblRapid:ENSBTAG00070017305
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
TRAP
Orthologs
human mouse all
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See ACP5 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (15911386..15915021, complement)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene calponin 1 Neighboring gene elongation factor 1 Neighboring gene uncharacterized LOC132345818 Neighboring gene zinc finger protein 709-like

Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Fluorometric method for measuring plasma tartrate-resistant acid phosphatase isoform 5b and its application in cattle. Yamagishi N, et al. J Vet Med Sci, 2009 Dec. PMID 20046032
  2. Association between changes in plasma calcium concentration and plasma tartrate-resistant acid phosphatase activity in periparturient cows. Sato J, et al. J Vet Med Sci, 2003 Feb. PMID 12655132
  3. ACP5 (Uteroferrin): phylogeny of an ancient and conserved gene expressed in the endometrium of mammals. Padua MB, et al. Biol Reprod, 2012 Apr. PMID 22278982, Free PMC Article
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Cows with a low tartrate-resistant acid phosphatase (TRAP) activity are at risk of developing milk fever in comparison to cows with high TRAP activity.
    Title: Association between changes in plasma calcium concentration and plasma tartrate-resistant acid phosphatase activity in periparturient cows.
  2. This study reported a fluorometric method for measuring tartrate-resistant acid phosphatase isoform 5b and reported on the activity in the blood of cattle through development.
    Title: Fluorometric method for measuring plasma tartrate-resistant acid phosphatase isoform 5b and its application in cattle.
Submit: New GeneRIF Correction

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acid phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ferric iron binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ferrous iron binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in bone resorption IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
tartrate-resistant acid phosphatase type 5
Names
acid phosphatase type 5
tartrate-resistant acid phosphatase
uteroferrin
NP_001243487.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256558.1 → NP_001243487.1  tartrate-resistant acid phosphatase type 5 precursor

    See identical proteins and their annotated locations for NP_001243487.1

    Status: VALIDATED

    Source sequence(s)
    DN287520, DY122872, EH160194, EV620389, EV620769
    UniProtKB/TrEMBL
    E1B8A0, G3M8V1
    Related
    ENSBTAP00070023161.1, ENSBTAT00070039034.1
    Conserved Domains (2) summary
    cd07378
    Location:32 → 317
    MPP_ACP5; Homo sapiens acid phosphatase 5 and related proteins, metallophosphatase domain
    pfam00149
    Location:32 → 248
    Metallophos; Calcineurin-like phosphoesterase

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    15911386..15915021 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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