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EEF1D eukaryotic translation elongation factor 1 delta [ Bos taurus (domestic cattle) ]

Gene ID: 516473, updated on 30-Jan-2025
Official Symbol
EEF1Dprovided by VGNC
Official Full Name
eukaryotic translation elongation factor 1 deltaprovided by VGNC
Primary source
VGNC:VGNC:53861
See related
EnsemblRapid:ENSBTAG00070011349
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See EEF1D in Genome Data Viewer
Location:
chromosome: 14
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 14 NC_037341.1 (1113581..1126356)

Chromosome 14 - NC_037341.1Genomic Context describing neighboring genes Neighboring gene pyrroline-5-carboxylate reductase 3 Neighboring gene tigger transposable element derived 5 Neighboring gene uncharacterized LOC132342144 Neighboring gene nicotinate phosphoribosyltransferase Neighboring gene maestro heat like repeat family member 6

Genomic Sequence:
NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Identification and expression pattern of two novel alternative splicing variants of EEF1D gene of dairy cattle. Xie Y, et al. Gene, 2014 Jan 25. PMID 24239553
  2. Regulation of DNA methylation on EEF1D and RPL8 expression in cattle. Liu X, et al. Genetica, 2017 Oct. PMID 28667419, Free PMC Article
  3. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
  4. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. result suggests that the DNA methylation of EEF1D plays an important role in the spatial and temporal regulation of its expression and possibly have an effect on the milk production traits
    Title: Regulation of DNA methylation on EEF1D and RPL8 expression in cattle.
  2. Findings present the first report on the alternative splicing of the bovine EEF1D gene.
    Title: Identification and expression pattern of two novel alternative splicing variants of EEF1D gene of dairy cattle.
Submit: New GeneRIF Correction

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in translational elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of eukaryotic translation elongation factor 1 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
elongation factor 1-delta
Names
EF-1-delta

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001206620.2 → NP_001193549.1  elongation factor 1-delta isoform 2

    See identical proteins and their annotated locations for NP_001193549.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (EEF1Da, PMID:24239553) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded protein (isoform 2) is shorter than isoform 1.
    Source sequence(s)
    BC105375, EV683636, EV704156, NKLS02000014
    UniProtKB/Swiss-Prot
    A5D989
    UniProtKB/TrEMBL
    A0A3Q1M9K4, L7R5X3
    Related
    ENSBTAP00070015448.1, ENSBTAT00070025814.1
    Conserved Domains (2) summary
    pfam00736
    Location:197 → 280
    EF1_GNE; EF-1 guanine nucleotide exchange domain
    pfam10587
    Location:159 → 185
    EF-1_beta_acid; Eukaryotic elongation factor 1 beta central acidic region

  2. NM_001289966.1 → NP_001276895.1  elongation factor 1-delta isoform 1

    See identical proteins and their annotated locations for NP_001276895.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    BC105375, EV704156, EW685785, NKLS02000014
    UniProtKB/TrEMBL
    A0A452DIM3, A0AAA9T5N1
    Related
    ENSBTAP00070015455.1, ENSBTAT00070025828.1
    Conserved Domains (2) summary
    pfam00736
    Location:554 → 637
    EF1_GNE; EF-1 guanine nucleotide exchange domain
    pfam10587
    Location:516 → 542
    EF-1_beta_acid; Eukaryotic elongation factor 1 beta central acidic region

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037341.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    1113581..1126356
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059893228.1 → XP_059749211.1  elongation factor 1-delta isoform X1

    UniProtKB/TrEMBL
    A0AAA9T5N1

  2. XM_005215199.3 → XP_005215256.3  elongation factor 1-delta isoform X2

    UniProtKB/TrEMBL
    A0AAA9T5N1

  3. XM_059893229.1 → XP_059749212.1  elongation factor 1-delta isoform X3

    UniProtKB/TrEMBL
    A0A452DIM3, A0AAA9T5N1
    Related
    ENSBTAP00070015420.1, ENSBTAT00070025764.1
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A5D989.2 GenPept UniProtKB/Swiss-Prot:A5D989

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.