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GET4 guided entry of tail-anchored proteins factor 4 [ Homo sapiens (human) ]

Gene ID: 51608, updated on 8-Nov-2020

Summary

Official Symbol
GET4provided by HGNC
Official Full Name
guided entry of tail-anchored proteins factor 4provided by HGNC
Primary source
HGNC:HGNC:21690
See related
Ensembl:ENSG00000239857 MIM:612056
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CEE; TRC35; CGI-20; C7orf20
Expression
Ubiquitous expression in testis (RPKM 20.0), adrenal (RPKM 15.8) and 25 other tissues See more
Orthologs

Genomic context

See GET4 in Genome Data Viewer
Location:
7p22.3
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (876554..896436)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (916191..936073)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene protein kinase cAMP-dependent type I regulatory subunit beta Neighboring gene dynein axonemal assembly factor 5 Neighboring gene Sad1 and UNC84 domain containing 1 Neighboring gene ArfGAP with dual PH domains 1 Neighboring gene cytochrome c oxidase assembly factor COX19

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: SUN1

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
chaperone binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
BAT3 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
BAT3 complex IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
Golgi to ER traffic protein 4 homolog
Names
H_NH1244M04.5
conserved edge expressed protein
conserved edge protein
golgi to ER traffic protein 4
transmembrane domain recognition complex 35 kDa subunit
transmembrane domain recognition complex, 35kDa

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015949.3NP_057033.2  Golgi to ER traffic protein 4 homolog

    See identical proteins and their annotated locations for NP_057033.2

    Status: VALIDATED

    Source sequence(s)
    AC073957, AL133014, BG109419, BM843540, BM980767
    Consensus CDS
    CCDS5317.1
    UniProtKB/Swiss-Prot
    Q7L5D6
    Related
    ENSP00000265857.3, ENST00000265857.8
    Conserved Domains (1) summary
    pfam04190
    Location:56302
    DUF410; Protein of unknown function (DUF410)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    876554..896436
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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