Format

Send to:

Choose Destination

CYRIB CYFIP related Rac1 interactor B [ Homo sapiens (human) ]

Gene ID: 51571, updated on 10-May-2020

Summary

Official Symbol
CYRIBprovided by HGNC
Official Full Name
CYFIP related Rac1 interactor Bprovided by HGNC
Primary source
HGNC:HGNC:25216
See related
Ensembl:ENSG00000153310 MIM:617978
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
L1; CYRI; BM-009; CYRI-B; FAM49B
Expression
Broad expression in bone marrow (RPKM 26.7), appendix (RPKM 26.4) and 24 other tissues See more
Orthologs

Genomic context

See CYRIB in Genome Data Viewer
Location:
8q24.21
Exon count:
23
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (129839593..130017129, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (130851839..131028897, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene CCDC26 long non-coding RNA Neighboring gene VISTA enhancer hs1709 Neighboring gene mitochondrial translational release factor 1 like pseudogene 2 Neighboring gene gasdermin C Neighboring gene ribosomal protein L15 pseudogene 12 Neighboring gene RNA, U7 small nuclear 181 pseudogene Neighboring gene microRNA 5194 Neighboring gene RNA, U6 small nuclear 1255, pseudogene Neighboring gene ASAP1 intronic transcript 2 Neighboring gene ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
A genome-wide association study identifies protein quantitative trait loci (pQTLs).
NHGRI GWA Catalog
Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder.
NHGRI GWA Catalog
Multiple loci are associated with white blood cell phenotypes.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp686B04128

Gene Ontology Provided by GOA

Function Evidence Code Pubs
MHC class Ib protein binding, via antigen binding groove ISS
Inferred from Sequence or Structural Similarity
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
small GTPase binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cellular response to molecule of bacterial origin IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of actin filament polymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of small GTPase mediated signal transduction IMP
Inferred from Mutant Phenotype
more info
PubMed 
platelet degranulation TAS
Traceable Author Statement
more info
 
positive regulation of T cell activation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of T cell activation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of T cell mediated cytotoxicity ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of interferon-gamma production ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of memory T cell activation ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of chemotaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of establishment of cell polarity IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of mitochondrial fission IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cilium ISS
Inferred from Sequence or Structural Similarity
more info
 
extracellular exosome HDA PubMed 
extracellular region TAS
Traceable Author Statement
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
platelet alpha granule lumen TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
CYFIP-related Rac1 interactor B; protein FAM49B
Names
FAM49B/JPH1 fusion
MTSS1/FAM49B fusion
family with sequence similarity 49 member B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256763.2NP_001243692.1  CYFIP-related Rac1 interactor B isoform 1

    See identical proteins and their annotated locations for NP_001243692.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) and variant 2 encode the same protein.
    Source sequence(s)
    AC022973, AK130372, BC003599, BX419336
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q9NUQ9
    UniProtKB/TrEMBL
    A0A024R9G4
    Related
    ENSP00000429499.1, ENST00000519540.5
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  2. NM_001330612.2NP_001317541.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AA975908, AC022973, CN362384, CX165551
    Consensus CDS
    CCDS83327.1
    UniProtKB/Swiss-Prot
    Q9NUQ9
    Related
    ENSP00000429978.1, ENST00000522250.5
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  3. NM_001353242.2NP_001340171.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an exon and includes three alternate exons in the 5' region, compared to variant 1.
    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Related
    ENSP00000384880.2, ENST00000401979.6
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  4. NM_001353243.2NP_001340172.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks two exons and includes three alternate exons in the 5' region, compared to variant 1.
    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Related
    ENSP00000429802.1, ENST00000523509.5
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  5. NM_001353244.2NP_001340173.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) includes two alternate internal exons, compared to variant 1.
    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS6361.1
    Related
    ENSP00000428117.1, ENST00000522746.5
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  6. NM_001353245.1NP_001340174.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  7. NM_001353246.1NP_001340175.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  8. NM_001353247.1NP_001340176.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  9. NM_001353248.2NP_001340177.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  10. NM_001353249.1NP_001340178.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  11. NM_001353250.1NP_001340179.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Related
    ENSP00000429078.1, ENST00000519110.5
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  12. NM_001353251.1NP_001340180.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  13. NM_001353252.1NP_001340181.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  14. NM_001353253.1NP_001340182.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  15. NM_001353254.2NP_001340183.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  16. NM_001353255.1NP_001340184.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  17. NM_001353256.2NP_001340185.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  18. NM_001353257.2NP_001340186.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  19. NM_001353258.2NP_001340187.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  20. NM_001353259.2NP_001340188.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  21. NM_001353260.2NP_001340189.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Related
    ENSP00000430674.1, ENST00000517654.5
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  22. NM_001353261.2NP_001340190.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  23. NM_001353262.2NP_001340191.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  24. NM_001353263.2NP_001340192.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  25. NM_001353264.2NP_001340193.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  26. NM_001353265.2NP_001340194.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  27. NM_001353266.2NP_001340195.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  28. NM_001353267.2NP_001340196.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  29. NM_001353268.2NP_001340197.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS6361.1
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  30. NM_001353269.1NP_001340198.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  31. NM_001353270.1NP_001340199.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  32. NM_001353271.1NP_001340200.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  33. NM_001353272.1NP_001340201.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  34. NM_001353273.1NP_001340202.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  35. NM_001353274.1NP_001340203.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  36. NM_001353275.1NP_001340204.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  37. NM_001353276.2NP_001340205.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  38. NM_001353277.1NP_001340206.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  39. NM_001353278.1NP_001340207.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  40. NM_001353279.1NP_001340208.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  41. NM_001353280.1NP_001340209.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  42. NM_001353281.1NP_001340210.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  43. NM_001353282.2NP_001340211.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  44. NM_001353283.2NP_001340212.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  45. NM_001353284.2NP_001340213.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  46. NM_001353285.2NP_001340214.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  47. NM_001353286.2NP_001340215.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  48. NM_001353287.2NP_001340216.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  49. NM_001353288.2NP_001340217.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  50. NM_001353289.2NP_001340218.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  51. NM_001353290.2NP_001340219.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  52. NM_001353291.2NP_001340220.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  53. NM_001353292.2NP_001340221.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  54. NM_001353293.2NP_001340222.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  55. NM_001353294.2NP_001340223.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  56. NM_001353295.2NP_001340224.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  57. NM_001353296.2NP_001340225.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  58. NM_001353297.2NP_001340226.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  59. NM_001353298.2NP_001340227.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  60. NM_001353299.2NP_001340228.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  61. NM_001353300.2NP_001340229.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  62. NM_001353301.2NP_001340230.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS83327.1
    Related
    ENSP00000430433.1, ENST00000522941.5
    Conserved Domains (1) summary
    pfam07159
    Location:1174
    DUF1394; Protein of unknown function (DUF1394)
  63. NM_001353302.1NP_001340231.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  64. NM_001353303.1NP_001340232.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  65. NM_001353304.1NP_001340233.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  66. NM_001353305.1NP_001340234.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  67. NM_001353306.2NP_001340235.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  68. NM_001353307.2NP_001340236.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  69. NM_001353308.1NP_001340237.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  70. NM_001353309.1NP_001340238.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  71. NM_001353310.2NP_001340239.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  72. NM_001353311.2NP_001340240.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568, KF495742
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  73. NM_001353312.2NP_001340241.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  74. NM_001353313.2NP_001340242.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  75. NM_001353314.2NP_001340243.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  76. NM_001353315.2NP_001340244.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  77. NM_001353316.2NP_001340245.1  CYFIP-related Rac1 interactor B isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Conserved Domains (1) summary
    pfam07159
    Location:17312
    DUF1394; Protein of unknown function (DUF1394)
  78. NM_016623.5NP_057707.3  CYFIP-related Rac1 interactor B isoform 1

    See identical proteins and their annotated locations for NP_057707.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC022973, AK130372, BX419336
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q9NUQ9
    UniProtKB/TrEMBL
    A0A024R9G4
    Related
    ENSP00000429150.1, ENST00000519824.6
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    129839593..130017129 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011517112.3XP_011515414.1  protein FAM49B isoform X1

    See identical proteins and their annotated locations for XP_011515414.1

    UniProtKB/Swiss-Prot
    Q9NUQ9
    UniProtKB/TrEMBL
    A0A024R9G4
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  2. XM_017013557.2XP_016869046.1  protein FAM49B isoform X2

    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  3. XM_011517121.3XP_011515423.1  protein FAM49B isoform X1

    See identical proteins and their annotated locations for XP_011515423.1

    UniProtKB/Swiss-Prot
    Q9NUQ9
    UniProtKB/TrEMBL
    A0A024R9G4
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  4. XM_017013551.2XP_016869040.1  protein FAM49B isoform X1

    UniProtKB/Swiss-Prot
    Q9NUQ9
    UniProtKB/TrEMBL
    A0A024R9G4
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  5. XM_017013554.2XP_016869043.1  protein FAM49B isoform X2

    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  6. XM_017013545.2XP_016869034.1  protein FAM49B isoform X1

    UniProtKB/Swiss-Prot
    Q9NUQ9
    UniProtKB/TrEMBL
    A0A024R9G4
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  7. XM_024447180.1XP_024302948.1  protein FAM49B isoform X1

    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
  8. XM_017013548.1XP_016869037.1  protein FAM49B isoform X1

    UniProtKB/Swiss-Prot
    Q9NUQ9
    UniProtKB/TrEMBL
    A0A024R9G4
    Conserved Domains (1) summary
    pfam07159
    Location:18320
    DUF1394; Protein of unknown function (DUF1394)
Support Center