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CARD11 caspase recruitment domain family member 11 [ Bos taurus (domestic cattle) ]

Gene ID: 515377, updated on 5-Sep-2025
Official Symbol
CARD11provided by VGNC
Official Full Name
caspase recruitment domain family member 11provided by VGNC
Primary source
VGNC:VGNC:26761
See related
BGD:BT22436; EnsemblRapid:ENSBTAG00070023772
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See CARD11 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (40415994..40523004)

Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene sidekick cell adhesion molecule 1 Neighboring gene microRNA mir-2390 Neighboring gene uncharacterized LOC132343886 Neighboring gene uncharacterized LOC112444339 Neighboring gene G protein subunit alpha 12 Neighboring gene archaelysin family metallopeptidase 1

Genomic Sequence:
NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Clone Names

  • MGC165904

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables CARD domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
caspase recruitment domain-containing protein 11

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109796.2 → NP_001103266.1  caspase recruitment domain-containing protein 11

    See identical proteins and their annotated locations for NP_001103266.1

    Status: PROVISIONAL

    Source sequence(s)
    BC153839
    UniProtKB/TrEMBL
    A0A3Q1M3P1, A8E646, F1MQU2
    Related
    ENSBTAP00070032163.1, ENSBTAT00070053543.1
    Conserved Domains (6) summary
    cd00992
    Location:672 → 744
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd08808
    Location:15 → 100
    CARD_CARD11_CARMA1; Caspase activation and recruitment domain of CARD11-like proteins
    pfam15743
    Location:295 → 430
    SPATA1_C; Spermatogenesis-associated C-terminus
    cl17036
    Location:769 → 831
    SH3; Src Homology 3 domain superfamily
    cl17182
    Location:161 → 288
    NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
    cl17190
    Location:1001 → 1135
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    40415994..40523004
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005225108.5 → XP_005225165.1  caspase recruitment domain-containing protein 11 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1M3P1
    Conserved Domains (5) summary
    cd00992
    Location:679 → 751
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd08808
    Location:22 → 107
    CARD_CARD11_CARMA1; Caspase activation and recruitment domain of CARD11-like proteins
    cl17036
    Location:776 → 838
    SH3; Src Homology 3 domain superfamily
    cl17190
    Location:1008 → 1142
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    cl25732
    Location:143 → 460
    SMC_N; RecF/RecN/SMC N terminal domain

  2. XM_005225109.5 → XP_005225166.1  caspase recruitment domain-containing protein 11 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1M3P1, A0A3S5ZPB2
    Conserved Domains (6) summary
    cd00992
    Location:673 → 745
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd08808
    Location:15 → 100
    CARD_CARD11_CARMA1; Caspase activation and recruitment domain of CARD11-like proteins
    pfam15743
    Location:295 → 430
    SPATA1_C; Spermatogenesis-associated C-terminus
    cl17036
    Location:770 → 832
    SH3; Src Homology 3 domain superfamily
    cl17182
    Location:161 → 288
    NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
    cl17190
    Location:1002 → 1136
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  3. XM_005225104.5 → XP_005225161.1  caspase recruitment domain-containing protein 11 isoform X1

    See identical proteins and their annotated locations for XP_005225161.1

    UniProtKB/TrEMBL
    A0A3Q1M3P1
    Conserved Domains (5) summary
    cd00992
    Location:680 → 752
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd08808
    Location:22 → 107
    CARD_CARD11_CARMA1; Caspase activation and recruitment domain of CARD11-like proteins
    cl17036
    Location:777 → 839
    SH3; Src Homology 3 domain superfamily
    cl17190
    Location:1009 → 1143
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    cl25732
    Location:143 → 460
    SMC_N; RecF/RecN/SMC N terminal domain

  4. XM_015460447.3 → XP_015315933.1  caspase recruitment domain-containing protein 11 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1M3P1
    Conserved Domains (5) summary
    cd00992
    Location:680 → 752
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd08808
    Location:22 → 107
    CARD_CARD11_CARMA1; Caspase activation and recruitment domain of CARD11-like proteins
    cl17036
    Location:777 → 839
    SH3; Src Homology 3 domain superfamily
    cl17190
    Location:1009 → 1143
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    cl25732
    Location:143 → 460
    SMC_N; RecF/RecN/SMC N terminal domain

  5. XM_005225105.5 → XP_005225162.1  caspase recruitment domain-containing protein 11 isoform X1

    See identical proteins and their annotated locations for XP_005225162.1

    UniProtKB/TrEMBL
    A0A3Q1M3P1
    Conserved Domains (5) summary
    cd00992
    Location:680 → 752
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd08808
    Location:22 → 107
    CARD_CARD11_CARMA1; Caspase activation and recruitment domain of CARD11-like proteins
    cl17036
    Location:777 → 839
    SH3; Src Homology 3 domain superfamily
    cl17190
    Location:1009 → 1143
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    cl25732
    Location:143 → 460
    SMC_N; RecF/RecN/SMC N terminal domain

  6. XM_059881294.1 → XP_059737277.1  caspase recruitment domain-containing protein 11 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1M3P1
    Related
    ENSBTAP00070032153.1, ENSBTAT00070053523.1

  7. XM_005225106.5 → XP_005225163.1  caspase recruitment domain-containing protein 11 isoform X1

    See identical proteins and their annotated locations for XP_005225163.1

    UniProtKB/TrEMBL
    A0A3Q1M3P1
    Related
    ENSBTAP00070032139.1, ENSBTAT00070053494.1
    Conserved Domains (5) summary
    cd00992
    Location:680 → 752
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd08808
    Location:22 → 107
    CARD_CARD11_CARMA1; Caspase activation and recruitment domain of CARD11-like proteins
    cl17036
    Location:777 → 839
    SH3; Src Homology 3 domain superfamily
    cl17190
    Location:1009 → 1143
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    cl25732
    Location:143 → 460
    SMC_N; RecF/RecN/SMC N terminal domain
Nucleotide Protein Strain
Heading Accession and Version

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