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TRIAP1 TP53 regulated inhibitor of apoptosis 1 [ Homo sapiens (human) ]

Gene ID: 51499, updated on 7-Jun-2020

Summary

Official Symbol
TRIAP1provided by HGNC
Official Full Name
TP53 regulated inhibitor of apoptosis 1provided by HGNC
Primary source
HGNC:HGNC:26937
See related
Ensembl:ENSG00000170855 MIM:614943
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
WF-1; MDM35; P53CSV; HSPC132
Expression
Ubiquitous expression in colon (RPKM 17.2), liver (RPKM 15.9) and 25 other tissues See more
Orthologs

Genomic context

See TRIAP1 in Genome Data Viewer
Location:
12q24.31
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (120443964..120446384, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (120881764..120884215, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene ribosomal protein S27 pseudogene 25 Neighboring gene Sharpr-MPRA regulatory region 3971 Neighboring gene cytochrome c oxidase subunit 6A1 Neighboring gene ribosomal protein L31 pseudogene 52 Neighboring gene glutamyl-tRNA amidotransferase subunit C Neighboring gene serine and arginine rich splicing factor 9

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study.
NHGRI GWA Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
p53 binding IPI
Inferred from Physical Interaction
more info
PubMed 
contributes_to phosphatidic acid transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
mitochondrial intermembrane space IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial intermembrane space TAS
Traceable Author Statement
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 
protein-containing complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
TP53-regulated inhibitor of apoptosis 1
Names
mitochondrial distribution and morphology 35 homolog
p53-inducible cell-survival factor
protein 15E1.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016399.3NP_057483.1  TP53-regulated inhibitor of apoptosis 1

    See identical proteins and their annotated locations for NP_057483.1

    Status: VALIDATED

    Source sequence(s)
    CB141335, U75688
    Consensus CDS
    CCDS9198.1
    UniProtKB/Swiss-Prot
    O43715
    Related
    ENSP00000449795.1, ENST00000546954.2
    Conserved Domains (1) summary
    pfam05254
    Location:258
    UPF0203; Uncharacterized protein family (UPF0203)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    120443964..120446384 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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