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SPOUT1 SPOUT domain containing methyltransferase 1 [ Homo sapiens (human) ]

Gene ID: 51490, updated on 17-Jun-2019

Summary

Official Symbol
SPOUT1provided by HGNC
Official Full Name
SPOUT domain containing methyltransferase 1provided by HGNC
Primary source
HGNC:HGNC:26933
See related
Ensembl:ENSG00000198917 MIM:617614
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CENP32; CENP-32; HSPC109; C9orf114
Expression
Ubiquitous expression in prostate (RPKM 7.5), lymph node (RPKM 6.8) and 25 other tissues See more
Orthologs

Genomic context

See SPOUT1 in Genome Data Viewer
Location:
9q34.11
Exon count:
13
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (128819651..128833309, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (131581930..131592299, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100506100 Neighboring gene zyg-11 related cell cycle regulator Neighboring gene TBC1 domain family member 13 Neighboring gene endonuclease G Neighboring gene kynurenine aminotransferase 1 Neighboring gene leucine rich repeat containing 8 VRAC subunit A Neighboring gene uncharacterized LOC101929291 Neighboring gene phytanoyl-CoA dioxygenase domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC29492, DKFZp566D143

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
miRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
miRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
maintenance of centrosome location IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
maintenance of centrosome location IMP
Inferred from Mutant Phenotype
more info
PubMed 
methylation IEA
Inferred from Electronic Annotation
more info
 
posttranscriptional regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
production of miRNAs involved in gene silencing by miRNA IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
production of miRNAs involved in gene silencing by miRNA IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
condensed chromosome kinetochore IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
kinetochore IDA
Inferred from Direct Assay
more info
PubMed 
mitotic spindle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic spindle IDA
Inferred from Direct Assay
more info
PubMed 
spindle pole centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spindle pole centrosome IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
putative methyltransferase C9orf114
Names
centromere protein 32
kinetochore-associated protein
NP_057474.2
XP_016870293.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016390.4NP_057474.2  putative methyltransferase C9orf114

    See identical proteins and their annotated locations for NP_057474.2

    Status: VALIDATED

    Source sequence(s)
    AL110193, AL441992, BC046133, BC063644, BM997763
    Consensus CDS
    CCDS6913.1
    UniProtKB/Swiss-Prot
    Q5T280
    Related
    ENSP00000354812.5, ENST00000361256.10
    Conserved Domains (1) summary
    pfam02598
    Location:75364
    Methyltrn_RNA_3; Putative RNA methyltransferase

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    128819651..128833309 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017014804.1XP_016870293.1  putative methyltransferase C9orf114 isoform X1

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