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LAT linker for activation of T cells [ Bos taurus (domestic cattle) ]

Gene ID: 514735, updated on 5-Sep-2025
Official Symbol
LATprovided by VGNC
Official Full Name
linker for activation of T cellsprovided by VGNC
Primary source
VGNC:VGNC:50054
See related
BGD:BT14502; EnsemblRapid:ENSBTAG00070020009
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See LAT in Genome Data Viewer
Location:
chromosome: 25
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (25862049..25866987, complement)

Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene proline-rich protein 13-like Neighboring gene tetraspanin-3-like Neighboring gene SPNS lysolipid transporter 1, lysophospholipid Neighboring gene nuclear factor of activated T cells 2 interacting protein

Genomic Sequence:
NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Clone Names

  • MGC157208

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of T cell activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in immunological synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
linker for activation of T-cells family member 1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001104978.1 → NP_001098448.1  linker for activation of T-cells family member 1 precursor

    See identical proteins and their annotated locations for NP_001098448.1

    Status: PROVISIONAL

    Source sequence(s)
    BC149498
    UniProtKB/TrEMBL
    A0AAA9TMJ4, A6QPU8
    Conserved Domains (1) summary
    pfam15234
    Location:27 → 254
    LAT; Linker for activation of T-cells

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    25862049..25866987 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010819416.4 → XP_010817718.1  linker for activation of T-cells family member 1 isoform X3

    UniProtKB/TrEMBL
    A0AAA9TMJ4
    Related
    ENSBTAP00070027164.1, ENSBTAT00070045151.1
    Conserved Domains (1) summary
    pfam15234
    Location:27 → 253
    LAT; Linker for activation of T-cells

  2. XM_005224906.5 → XP_005224963.1  linker for activation of T-cells family member 1 isoform X2

    See identical proteins and their annotated locations for XP_005224963.1

    UniProtKB/TrEMBL
    A0AAA9TMJ4
    Conserved Domains (1) summary
    pfam15234
    Location:27 → 279
    LAT; Linker for activation of T-cells

  3. XM_005224905.5 → XP_005224962.1  linker for activation of T-cells family member 1 isoform X1

    See identical proteins and their annotated locations for XP_005224962.1

    UniProtKB/TrEMBL
    A0AAA9TMJ4, F1MZ60
    Related
    ENSBTAP00070027171.1, ENSBTAT00070045166.1
    Conserved Domains (1) summary
    pfam15234
    Location:27 → 280
    LAT; Linker for activation of T-cells
Nucleotide Protein Strain
Heading Accession and Version

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