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RHCG Rh family C glycoprotein [ Homo sapiens (human) ]

Gene ID: 51458, updated on 23-Dec-2018

Summary

Official Symbol
RHCGprovided by HGNC
Official Full Name
Rh family C glycoproteinprovided by HGNC
Primary source
HGNC:HGNC:18140
See related
Ensembl:ENSG00000140519 MIM:605381
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RHGK; PDRC2; C15orf6; SLC42A3
Expression
Restricted expression toward esophagus (RPKM 1491.4) See more
Orthologs

Genomic context

See RHCG in Genome Data Viewer
Location:
15q26.1
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 15 NC_000015.10 (89471407..89496613, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (90014638..90039799, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC105370964 Neighboring gene uncharacterized LOC112268153 Neighboring gene long intergenic non-protein coding RNA 928 Neighboring gene TOPBP1 interacting checkpoint and replication regulator Neighboring gene kinesin family member 7

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ammonium transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ammonium transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
ammonium transmembrane transporter activity IGI
Inferred from Genetic Interaction
more info
PubMed 
ammonium transmembrane transporter activity TAS
Traceable Author Statement
more info
 
ankyrin binding IDA
Inferred from Direct Assay
more info
PubMed 
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
amine transport NAS
Non-traceable Author Statement
more info
PubMed 
ammonium transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ammonium transport IDA
Inferred from Direct Assay
more info
PubMed 
ammonium transport IGI
Inferred from Genetic Interaction
more info
PubMed 
cellular ion homeostasis IDA
Inferred from Direct Assay
more info
PubMed 
epithelial cell differentiation NAS
Non-traceable Author Statement
more info
PubMed 
homeostatic process NAS
Non-traceable Author Statement
more info
PubMed 
regulation of pH IEA
Inferred from Electronic Annotation
more info
 
transepithelial ammonium transport IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
basolateral plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 
extracellular exosome HDA PubMed 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
ammonium transporter Rh type C
Names
Rh type C glycoprotein
Rhesus blood group, C glycoprotein
rh family type C glycoprotein
rh glycoprotein kidney
rhesus blood group family type C glycoprotein
tumor-related protein DRC2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001321041.1NP_001307970.1  ammonium transporter Rh type C

    Status: VALIDATED

    Source sequence(s)
    AK313238, BC015461
    Consensus CDS
    CCDS10351.1
    UniProtKB/Swiss-Prot
    Q9UBD6
    Conserved Domains (1) summary
    cl03012
    Location:60435
    Ammonium_transp; Ammonium Transporter Family
  2. NM_016321.3NP_057405.1  ammonium transporter Rh type C

    See identical proteins and their annotated locations for NP_057405.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes a protein.
    Source sequence(s)
    AF193809, BC030965, DC306265
    Consensus CDS
    CCDS10351.1
    UniProtKB/Swiss-Prot
    Q9UBD6
    Related
    ENSP00000268122.4, ENST00000268122.8
    Conserved Domains (1) summary
    cl03012
    Location:60435
    Ammonium_transp; Ammonium Transporter Family

RNA

  1. NR_110261.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the use of an alternate 3' splice site, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AF193809, BC015461, DC306265
    Related
    ENST00000560081.5

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p12 Primary Assembly

    Range
    89471407..89496613 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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