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GULP1 GULP PTB domain containing engulfment adaptor 1 [ Homo sapiens (human) ]

Gene ID: 51454, updated on 4-Jul-2021

Summary

Official Symbol
GULP1provided by HGNC
Official Full Name
GULP PTB domain containing engulfment adaptor 1provided by HGNC
Primary source
HGNC:HGNC:18649
See related
Ensembl:ENSG00000144366 MIM:608165
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CED6; GULP; CED-6
Summary
The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene. [provided by RefSeq, Nov 2011]
Expression
Broad expression in endometrium (RPKM 8.3), prostate (RPKM 7.5) and 22 other tissues See more
Orthologs
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Genomic context

See GULP1 in Genome Data Viewer
Location:
2q32.1-q32.2
Exon count:
21
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (188291699..188595926)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (189156601..189460653)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 1090 Neighboring gene chromosome 18 open reading frame 25 pseudogene Neighboring gene Sharpr-MPRA regulatory region 8257 Neighboring gene RNA, 5S ribosomal pseudogene 114 Neighboring gene microRNA 561 Neighboring gene uncharacterized LOC105373790 Neighboring gene disrupted in renal carcinoma 1 Neighboring gene uncharacterized LOC105373791 Neighboring gene microRNA 1245a Neighboring gene microRNA 1245b Neighboring gene collagen type III alpha 1 chain

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp120 env Upregulation of apoptosis genes such as NCK-associated protein 1, PTB domain adaptor protein CED-6, and TNF receptor superfamily 5 are induced by HIV-1 gp120 in human neurons PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ31156

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in lipid transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within phagocytosis, engulfment IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
PTB domain-containing engulfment adapter protein 1
Names
GULP, engulfment adaptor PTB domain containing 1
PTB domain adapter protein CED-6
PTB domain adaptor protein CED-6
cell death protein 6 homolog
engulfment adapter protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252668.2NP_001239597.1  PTB domain-containing engulfment adapter protein 1 isoform b

    See identical proteins and their annotated locations for NP_001239597.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) contains an alternate exon in the 3' end, that causes a frameshift. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Consensus CDS
    CCDS58742.1
    UniProtKB/Swiss-Prot
    Q9UBP9
    Related
    ENSP00000387144.1, ENST00000409843.5
    Conserved Domains (2) summary
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
    pfam10211
    Location:136198
    Ax_dynein_light; Axonemal dynein light chain
  2. NM_001252669.2NP_001239598.1  PTB domain-containing engulfment adapter protein 1 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame coding segment compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Consensus CDS
    CCDS58743.1
    UniProtKB/Swiss-Prot
    Q9UBP9
    Related
    ENSP00000387171.1, ENST00000409805.5
    Conserved Domains (2) summary
    cd14686
    Location:6092
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cl17171
    Location:3154
    PH-like; Pleckstrin homology-like domain
  3. NM_001375925.1NP_001362854.1  PTB domain-containing engulfment adapter protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4), as well as variants 1, 5, and 6-10, encodes isoform a.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Related
    ENSP00000352047.3, ENST00000359135.7
    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  4. NM_001375926.1NP_001362855.1  PTB domain-containing engulfment adapter protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5), as well as variants 1, 4, and 6-10, encodes isoform a.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Related
    ENSP00000386289.1, ENST00000409580.5
    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  5. NM_001375927.1NP_001362856.1  PTB domain-containing engulfment adapter protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6), as well as variants 1, 4, 5, and 7-10, encodes isoform a.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  6. NM_001375928.1NP_001362857.1  PTB domain-containing engulfment adapter protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7), as well as variants 1, 4-6, and 8-10, encodes isoform a.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  7. NM_001375929.1NP_001362858.1  PTB domain-containing engulfment adapter protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8), as well as variants 1, 4-7, 9, and 10, encodes isoform a.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  8. NM_001375930.1NP_001362859.1  PTB domain-containing engulfment adapter protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9), as well as variants 1, 4-8, and 10, encodes isoform a.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  9. NM_001375931.1NP_001362860.1  PTB domain-containing engulfment adapter protein 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10), as well as variants 1 and 4-9, encodes isoform a.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  10. NM_001375932.1NP_001362861.1  PTB domain-containing engulfment adapter protein 1 isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11), as well as variants 12-18, encodes isoform d.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
    cl40461
    Location:150191
    ZIP_TSC22D-like; leucine zipper found in the TSC22 domain leucine zipper transcription factors, c-Myc-binding protein, and similar proteins
  11. NM_001375933.1NP_001362862.1  PTB domain-containing engulfment adapter protein 1 isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12), as well as variants 11 and 13-18, encodes isoform d.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
    cl40461
    Location:150191
    ZIP_TSC22D-like; leucine zipper found in the TSC22 domain leucine zipper transcription factors, c-Myc-binding protein, and similar proteins
  12. NM_001375934.1NP_001362863.1  PTB domain-containing engulfment adapter protein 1 isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13), as well as variants 11, 12, and 14-18, encodes isoform d.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
    cl40461
    Location:150191
    ZIP_TSC22D-like; leucine zipper found in the TSC22 domain leucine zipper transcription factors, c-Myc-binding protein, and similar proteins
  13. NM_001375935.1NP_001362864.1  PTB domain-containing engulfment adapter protein 1 isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14), as well as variants 11-13 and 15-18, encodes isoform d.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
    cl40461
    Location:150191
    ZIP_TSC22D-like; leucine zipper found in the TSC22 domain leucine zipper transcription factors, c-Myc-binding protein, and similar proteins
  14. NM_001375936.1NP_001362865.1  PTB domain-containing engulfment adapter protein 1 isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15), as well as variants 11-14 and 16-18, encodes isoform d.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
    cl40461
    Location:150191
    ZIP_TSC22D-like; leucine zipper found in the TSC22 domain leucine zipper transcription factors, c-Myc-binding protein, and similar proteins
  15. NM_001375937.1NP_001362866.1  PTB domain-containing engulfment adapter protein 1 isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16), as well as variants 11-15, 17, and 18, encodes isoform d.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
    cl40461
    Location:150191
    ZIP_TSC22D-like; leucine zipper found in the TSC22 domain leucine zipper transcription factors, c-Myc-binding protein, and similar proteins
  16. NM_001375938.1NP_001362867.1  PTB domain-containing engulfment adapter protein 1 isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17), as well as variants 11-16 and 18, encodes isoform d.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
    cl40461
    Location:150191
    ZIP_TSC22D-like; leucine zipper found in the TSC22 domain leucine zipper transcription factors, c-Myc-binding protein, and similar proteins
  17. NM_001375939.1NP_001362868.1  PTB domain-containing engulfment adapter protein 1 isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18), as well as variants 11-17, encodes isoform d.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
    cl40461
    Location:150191
    ZIP_TSC22D-like; leucine zipper found in the TSC22 domain leucine zipper transcription factors, c-Myc-binding protein, and similar proteins
  18. NM_001375940.1NP_001362869.1  PTB domain-containing engulfment adapter protein 1 isoform e

    Status: REVIEWED

    Description
    Transcript Variant: This variant (19), as well as variants 20-22, encodes isoform e.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (1) summary
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  19. NM_001375941.1NP_001362870.1  PTB domain-containing engulfment adapter protein 1 isoform e

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20), as well as variants 19, 21, and 22, encodes isoform e.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (1) summary
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  20. NM_001375942.1NP_001362871.1  PTB domain-containing engulfment adapter protein 1 isoform e

    Status: REVIEWED

    Description
    Transcript Variant: This variant (21), as well as variants 19, 20, and 22, encodes isoform e.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (1) summary
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  21. NM_001375943.1NP_001362872.1  PTB domain-containing engulfment adapter protein 1 isoform e

    Status: REVIEWED

    Description
    Transcript Variant: This variant (22), as well as variants 19-21, encodes isoform e.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (1) summary
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  22. NM_001375944.1NP_001362873.1  PTB domain-containing engulfment adapter protein 1 isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (23), as well as variants 24-26, encodes isoform f.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    TIGR02168
    Location:71154
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cl17171
    Location:14111
    PH-like; Pleckstrin homology-like domain
  23. NM_001375945.1NP_001362874.1  PTB domain-containing engulfment adapter protein 1 isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (24), as well as variants 23, 25, and 26, encodes isoform f.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    TIGR02168
    Location:71154
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cl17171
    Location:14111
    PH-like; Pleckstrin homology-like domain
  24. NM_001375946.1NP_001362875.1  PTB domain-containing engulfment adapter protein 1 isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (25), as well as variants 23, 24, and 26, encodes isoform f.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    TIGR02168
    Location:71154
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cl17171
    Location:14111
    PH-like; Pleckstrin homology-like domain
  25. NM_001375947.1NP_001362876.1  PTB domain-containing engulfment adapter protein 1 isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (26), as well as variants 23-25, encodes isoform f.
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    TIGR02168
    Location:71154
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cl17171
    Location:14111
    PH-like; Pleckstrin homology-like domain
  26. NM_001375948.1NP_001362877.1  PTB domain-containing engulfment adapter protein 1 isoform g

    Status: REVIEWED

    Description
    Transcript Variant: This variant (27), as well as variant 28, encodes the longest isoform (g).
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  27. NM_001375949.1NP_001362878.1  PTB domain-containing engulfment adapter protein 1 isoform g

    Status: REVIEWED

    Description
    Transcript Variant: This variant (28), as well as variant 27, encodes the longest isoform (g).
    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  28. NM_001375950.1NP_001362879.1  PTB domain-containing engulfment adapter protein 1 isoform h

    Status: REVIEWED

    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    TIGR02168
    Location:71154
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cl17171
    Location:14111
    PH-like; Pleckstrin homology-like domain
  29. NM_001375951.1NP_001362880.1  PTB domain-containing engulfment adapter protein 1 isoform i

    Status: REVIEWED

    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd01273
    Location:3129
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
    pfam10211
    Location:108178
    Ax_dynein_light; Axonemal dynein light chain
  30. NM_001375952.1NP_001362881.1  PTB domain-containing engulfment adapter protein 1 isoform j

    Status: REVIEWED

    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (2) summary
    cd14686
    Location:139171
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14133
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  31. NM_001375953.1NP_001362882.1  PTB domain-containing engulfment adapter protein 1 isoform k

    Status: REVIEWED

    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
    Conserved Domains (1) summary
    cl17171
    Location:14111
    PH-like; Pleckstrin homology-like domain
  32. NM_016315.4NP_057399.1  PTB domain-containing engulfment adapter protein 1 isoform a

    See identical proteins and their annotated locations for NP_057399.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1), as well as variants 4, 5, and 6-10, encodes isoform a.
    Source sequence(s)
    AC092598, AF200715, AK055718, AK314498, AL080142
    Consensus CDS
    CCDS2295.1
    UniProtKB/Swiss-Prot
    Q9UBP9
    Related
    ENSP00000386732.1, ENST00000409830.6
    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain

RNA

  1. NR_164744.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490
  2. NR_164745.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC092598, AC104131, AC108493, AC125490

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    188291699..188595926
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011511332.2XP_011509634.1  PTB domain-containing engulfment adapter protein 1 isoform X5

    Conserved Domains (2) summary
    cd14686
    Location:135167
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:3129
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  2. XM_011511333.1XP_011509635.1  PTB domain-containing engulfment adapter protein 1 isoform X6

    See identical proteins and their annotated locations for XP_011509635.1

    Conserved Domains (2) summary
    cd14686
    Location:117149
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cl17171
    Location:14111
    PH-like; Pleckstrin homology-like domain
  3. XM_011511329.1XP_011509631.1  PTB domain-containing engulfment adapter protein 1 isoform X2

    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  4. XM_006712589.3XP_006712652.1  PTB domain-containing engulfment adapter protein 1 isoform X7

    Conserved Domains (3) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
    pfam04880
    Location:167246
    NUDE_C; NUDE protein, C-terminal conserved region
  5. XM_011511335.2XP_011509637.1  PTB domain-containing engulfment adapter protein 1 isoform X9

    Conserved Domains (3) summary
    cd14686
    Location:117149
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    pfam04880
    Location:121200
    NUDE_C; NUDE protein, C-terminal conserved region
    cl17171
    Location:14111
    PH-like; Pleckstrin homology-like domain
  6. XM_006712582.1XP_006712645.1  PTB domain-containing engulfment adapter protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006712645.1

    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  7. XM_017004307.1XP_016859796.1  PTB domain-containing engulfment adapter protein 1 isoform X9

    Conserved Domains (3) summary
    cd14686
    Location:117149
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    pfam04880
    Location:121200
    NUDE_C; NUDE protein, C-terminal conserved region
    cl17171
    Location:14111
    PH-like; Pleckstrin homology-like domain
  8. XM_006712580.4XP_006712643.1  PTB domain-containing engulfment adapter protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006712643.1

    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  9. XM_006712584.4XP_006712647.1  PTB domain-containing engulfment adapter protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006712647.1

    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  10. XM_006712583.4XP_006712646.1  PTB domain-containing engulfment adapter protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006712646.1

    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  11. XM_017004306.1XP_016859795.1  PTB domain-containing engulfment adapter protein 1 isoform X8

    UniProtKB/Swiss-Prot
    Q9UBP9
    Related
    ENSP00000386867.1, ENST00000409609.5
    Conserved Domains (2) summary
    cd14686
    Location:163195
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:14157
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain
  12. XM_011511331.1XP_011509633.1  PTB domain-containing engulfment adapter protein 1 isoform X4

    Conserved Domains (2) summary
    cd14686
    Location:150182
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    cd01273
    Location:5144
    PTB_CED-6; Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain

RNA

  1. XR_002959305.1 RNA Sequence

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