CXCL9 C-X-C motif chemokine ligand 9 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: CXCL9provided by VGNC
Official Full Name: C-X-C motif chemokine ligand 9provided by VGNC
Primary source: VGNC:VGNC:27854
See related: BGD:BT11117; EnsemblRapid:ENSBTAG00070002964
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	6	NC_037333.1 (90858580..90863225, complement)

Chromosome 6 - NC_037333.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CXCK9 and CXCL10 chemokines displayed a trend of decreasing mRNA expression as lesion progressed, suggesting a higher level of importance during the early stages of the immune response to mycobacterial infection.
Title: Upregulation of IL-17A, CXCL9 and CXCL10 in early-stage granulomas induced by Mycobacterium bovis in cattle.
This report describes the cloning and characterization of expressed gene sequences of bovine, equine, and swine CXCL9 from RNA obtained from peripheral blood mononuclear cells and other tissues.
Title: Expressed gene sequence of the IFNγ-response chemokine CXCL9 of cattle, horses, and swine.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables chemokine activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in defense response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: C-X-C motif chemokine 9

Names: monokine induced by interferon gamma; small-inducible cytokine B9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001113172.1 → NP_001106643.1 C-X-C motif chemokine 9 precursor

See identical proteins and their annotated locations for NP_001106643.1

Status: PROVISIONAL

Source sequence(s)

EU276061

UniProtKB/Swiss-Prot

A9QWP9

Related

ENSBTAP00070003915.1, ENSBTAT00070006800.1

Conserved Domains (1) summary

cd00273
Location:27 → 90

Chemokine_CXC; Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members ...